Xs: 6.438944 Ys: -0.9111425 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: BIOLOGY AND LIFE TABLE OF FALL ARMYWORM, Spodoptera frugiperda (J.E. SMITH) (LEPIDOPTERA: NOCTUIDAE) ON MAIZE AND RICE abstract: The fall armyworm, Spodoptera frugiperda (J.E. Smith), is an invasive pest that causes heavy damage to maize in Indonesia and other countries. This is a polyphagous pest attacking more than 300 host plants species, especially on the Poaceae family, such as maize and rice. The biology and life table of S. frugiperda are important for predicting increases in field population and determining the appropriate timing and control techniques. This study was aimed to determine the development period, survival, reproduction, and life table of S. frugiperda on maize and rice. It was conducted in the laboratory under two treatments namely maize-fed larvae and rice-fed larvae, replicated three times, with a total number of 300 individuals observed. The results showed that the type of host plant significantly affected the biology and life table of S. frugiperda. The larvae of S. frugiperda that fed on maize had a larger body size than those fed on rice. The life table of S. frugiperda in both maize and rice was 32.24 and 37.90 days, respectively. Meanwhile, the female longevity at 25.7 o C from the egg until imagos death on maize and rice was 44.55 and 50.25 days, and 43.79 and 48.61 days for males, respectively. The fecundity was higher for maize-fed larvae at 261.88 eggs per female compared to rice-fed at 172.36 eggs per female. The intrinsic rate (rm) was significantly different between the two hosts, with a higher rate of 0.209 individual per parent per day on maize-fed compared to the rice-fed larvae at 0.154 individual per parent per day. The maximum values of rm alongside the net reproductive rate (Ro), the finite rate of increase (λ), the shortest mean generation time (T), and doubling time (DT) was also calculated, which indicated that maize was more favorable for the life of S. frugiperda. These findings are useful for predicting the development of S. frugiperda populations on both host plants and that they can be used as references to determine appropriate control. Serangga 2021, 26(4): 161-174. Maharani et al. ISSN 1394-5130 162 ABSTRAK Ulat Ratus, Spodoptera frugiperda (J.E. Smith) merupakan perosak invasif yang menyebabkan kerosakan besar pada jagung di Indonesia dan negara lain. Perosak polifagus ini mempunyai lebih daripada 300 spesies tanaman perumah, terutama dari famili Poaceae seperti jagung dan padi. Biologi dan jadual hidup S. frugiperda adalah penting untuk meramalkan peningkatan populasi FAW di lapangan bagi menentukan teknik dan masa kawalan yang sesuai. Kajian ini bertujuan untuk menentukan tempoh perkembangan, kelangsungan hidup, pembiakan dan jadual hidup S. frugiperda yang memakan jagung dan padi. Kajian dilakukan di makmal, setiap dua rawatan iaitu larva yang diberi makan jagung dan larva yang diberi makan padi direplikasi tiga kali dengan jumlah individu yang diperhatikan adalah 300 individu. Hasil kajian menunjukkan jenis tanaman perumah mempengaruhi biologi dan jadual hidup S. frugiperda. Larva S. frugiperda yang memakan jagung mempunyai ukuran badan yang lebih besar dari yang memakan padi. Kitaran hidup S. frugiperda di dua tanaman (jagung dan padi) masing-masing adalah 32.24 dan 37.90 hari. Jangka hayat betina lebih panjang pada suhu 25.7 o C dari telur sehingga betina mati ketika diberi makan jagung dan diberi makan padi pada masing-masing 44.55 dan 50.25 hari, dan 43.79 dan 48.61 hari untuk jantan. Fekunditi lebih tinggi untuk larva yang diberi makan jagung (261.88 telur per betina) berbanding dengan padi (172.36 telur per betina). Kadar intrinsik (rm) jauh berbeza antara kedua-dua perumah, dengan kadar yang lebih tinggi (0.209 individu setiap pasangan setiap hari) pada makan jagung berbanding dengan makan padi (0.154 individu setiap pasangan setiap hari). Nilai maksimum rm bersama dengan kadar pembiakan bersih (Ro) dan kadar kenaikan terhingga (λ), dan masa penjanaan min terpendek (T) dan masa penggandaan (DT) juga dikira, menunjukkan bahawa jagung adalah baik untuk kehidupan S. frugiperda. Hasil penemuan ini bermanfaat untuk menjangkakan perkembangan populasi S. frugiperda pada kedua tanaman perumah untuk dijadikan rujukan bagi menentukan pengendalian yang tepat.


Xs: 3.6130297 Ys: 0.21112832 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Opposing Democracy in the Digital Age: The Yellow Shirts in Thailand abstract: Opposing Democracy in the Digital Age is about why ordinary people in a democratizing state oppose democracy and how they leverage both traditional and social media to do so. Aim Sinpeng focuses on the people behind popular, large-scale antidemocratic movements that helped bring down democracy in 2006 and 2014 in Thailand. The yellow shirts (PAD—People’s Alliance for Democracy) that are the focus of the book are antidemocratic movements grown out of democratic periods in Thailand, but became the catalyst for the country’s democratic breakdown. Why, when, and how supporters of these movements mobilize offline and online to bring down democracy are some of the key questions that Sinpeng answers. While the book primarily uses a qualitative methodological approach, it also uses several quantitative tools to analyze social media data in the later chapters. This is one of few studies in the field of regime transition that focuses on antidemocratic mobilization and takes the role of social media seriously.


Xs: 6.2143254 Ys: -1.195435 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: The contribution of dietary restriction to extended longevity in the malaria vector Anopheles coluzzii abstract: Background
Variation in longevity has long been of interest in vector biology because of its implication in disease transmission through vectorial capacity. Recent studies suggest that Anopheles coluzzii adults persist during the ~7 month dry season via aestivation. Recently there has been a growing body of evidence linking dietary restriction and low ratio of dietary protein to carbohydrate with extended longevity of animals. Here, we evaluated the effects of dietary restriction and the protein : carbohydrate ratio on longevity of An. coluzzii. ResultsIn our experiment, we combined dietary regimes with temperature and relative humidity to assess their effects on An. coluzzii longevity, in an attempt to simulate aestivation under laboratory conditions. Our results showed significant effects of both the physical and the dietary variables on longevity, but that diet regimen had a considerably greater effect than those of the physical conditions. Higher temperature and lower humidity reduced longevity. At 22 °C dietary protein (blood) shortened longevity when sugar was not restricted (RH = 85%), but extended longevity when sugar was restricted (RH = 50%). Conclusions
Dietary restriction extended longevity in accord with predictions, but protein : carbohydrate ratio had a negligible effect. We identified conditions that significantly extend longevity in malaria vectors, however, the extent of increase in longevity was insufficient to simulate aestivation.


Xs: 3.5195477 Ys: -0.13583492 Publish year: 2018 keyword: thai__longevity_diet source: Thai title: Optimizing nutrition in older people abstract: Older adults are at increased risk of malnutrition, for a variety of physiological and psychological reasons. This has implications for health, quality of life, independence and economic circumstances. Improvements in nutrition are known to bring tangible benefits to older people and many age-related diseases and conditions can be prevented, modulated or ameliorated by good nutrition. However, practical and realistic approaches are required to optimize diet and food intake in older adults. One area where improvements can be made relates to appetite. Encouraging older adults to prepare meals can increase appetite and food intake, and providing opportunities for older adults to eat a wide variety of foods, in company, is a simple strategy to increase food intake.
The protein requirement of older adults is subject to controversy and although considered the most satiating macronutrient, it appears that protein does not elicit as great a satiating effect in older adults as it does in younger individuals. This indicates that there is potential to increase protein intake without impacting on overall energy intake. Other areas where simple practical improvements can be made include both packaging of foods that are easy to prepare and the education of older adults on the safe storage and preparation of food. Research into improving the diets and nutritional status of older adults has indicated that many of the strategies can be easily and cost-effectively undertaken.


Xs: 3.5547779 Ys: 0.4200519 Publish year: 2009 keyword: thai__longevity_diet source: Thai title: Cultural resistance to fast-food consumption? A study of youth in North Eastern Thailand abstract: Increased intake of saturated fat and refined sugars underlies much of the problem of emerging obesity all over the world. This includes middle-income countries like Thailand, which are subject to successful marketing of Western fast foods especially targeted at adolescents. In this study we explore the socio-cultural influences on fast-food intake for non-metropolitan (rural and urban) adolescents in North East Thailand (Isan). Our questionnaire sample included 634 persons aged 15-19 years who are in and out of formal schooling and who are randomly representing upper, central and lower Isan. All were asked about their knowledge of fast-food health risks and their attitudes towards, and consumption of, fast food and traditional food. As well, we used several focus groups to obtain qualitative data to complement the information derived from the questionnaire. Some three quarters of sampled youth were aware that fast food causes obesity and half knew of the link to heart disease. About half consumed fast food regularly, induced by the appeal of 'modern' lifestyles, social events and marketing, as well as by the convenience, speed and taste. Nearly two-thirds thought that local foods should be more popular and these beliefs were more likely to be found among children from educated and urban families. Local foods already constitute a cultural resistance to fast-food uptake. We propose several methods to boost this resistance and protect the youth of Thailand against fast food and its many adverse health consequences.


Xs: 3.9479063 Ys: 0.26293397 Publish year: 2014 keyword: thai__longevity_diet source: Thai title: The Effects of Health Consciousness and Familiarity with DTCA on Perceptions of Dietary Supplements abstract: This study examines the effect of consumer health-consciousness on attitude toward dietary supplements as well as consumer perceptions of supplement risks and benefits when compared to their prescription drug counterparts. The authors investigate three conditions (insomnia, depression, and high cholesterol) with both a prescription drug and dietary supplement regimen available. Results indicate that health consciousness is positively related to attitudes toward dietary supplements, which is positively related to perceived supplement benefits, but negatively associated with perceived supplement risks. Mediating effects of attitudes toward dietary supplements are also found. Moreover, familiarity with direct to consumer advertising (DTCA) moderates the relationship between health consciousness and attitude toward dietary supplements. Our findings suggest that knowledge may play a key role in attitude and perception formation and that both benefit and risk information about supplements should be provided to consumers so they can make informed decisions about their health.


Xs: 4.28432 Ys: -0.15189792 Publish year: 2020 keyword: thai__longevity_diet source: Thai title: Genetic evaluation of sow survival in Thailand commercial farms using random regression models abstract: The aims of this study were 1) estimate heritability and variance components for sow survival traits using random regression model and 2) to identify the best model when conducting a sow survival genetic evaluation for Thailand commercial farms by comparing RRM with different covariance functions (Legendre polynomial and linear spline). A total of 11,595 and 11,336 sows from Landrace and Large White sows, respectively, were used to compare random regression models. The model using a second to third order Legendre polynomial for additive genetic effects and second to fourth order Legendre polynomial for permanent environmental effects (LG22, LG23, LG33 and LG34) and linear splines 3 to 4 knots for additive genetic effects and permanent environmental effects (SPL33 and SPL44) were used for analyses of genetic parameters. Bayesian interference using Gibbs sampling was used to estimate all covariance components. The model that included Legendre polynomial functions LG22 provided the lowest the deviance information criterion (DIC), provide the best fit for both the Landrace and Large White datasets. The heritability estimates for sow survival obtained with LG22 (the best fit model) ranged from 0.12 to 0.15 and 0.14 to 0.18 for Landrace and Large White sows, respectively. The genetic correlation among sow survival obtained with LG22 (the best fit model) ranged from 0.27 to 0.99, 0.43 to 0.99 for Landrace and Large White sows, respectively. Results from this study indicate that RRM could be used for genetic evaluation of sow survival.


Xs: 4.6141515 Ys: 0.9605241 Publish year: 2012 keyword: thai__longevity_diet source: Thai title: A Survey of Complementary and Alternative Medicine Use in Cancer Patients Treated with Radiotherapy in Thailand abstract: Introduction. Use of complementary and alternative medicine (CAM) in cancer patients is increasingly acceptable worldwide, but most of the studies were surveyed from developed countries. In this study, we evaluated the first and large cohort of cancer patients with CAM use in Thailand. Materials and Methods. A self-administered questionnaire was completed by 248 cancer patients attending outpatient radiotherapy unit at Ramathibodi Hospital. Results. The prevalence of CAM use was 60.9%. The most frequently used CAM were dietary/vitamin supplements (56.9%). Independent predictors of CAM use were high income (P < 0.001) and cancer type (P = 0.019). About half of the patients (51%) reported positive effects from CAM use. Nevertheless, 9.4% of the patient also reported side effects. The majority of patients (58.3%) did not disclose their use of CAM to their doctors because they felt that it was not necessary for doctors to know (65.9%). The average spending for CAM use was 200 USD/month (range, 10-1,000). Conclusion. Although the cost for CAM is relatively expensive, the prevalence of CAM use in cancer patients in Thailand is high particularly, in patients with higher income. Therefore, all clinical oncologists should be concerned about the use of CAM during evaluation of the cancer patients.


Xs: 3.0643334 Ys: 3.772984 Publish year: 2022 keyword: thai__longevity_diet source: Thai title: Probiotics Supplementation Improves Intestinal Permeability, Obesity Index and Metabolic Biomarkers in Elderly Thai Subjects: A Randomized Controlled Trial abstract: Intestinal integrity prevents the diffusion of allergens, toxins, and pathogens from the
gastrointestinal lumen into the tissue and the circulatory system. Damage in intestinal integrity may cause mild to serious health issues, such as inflammation, gastrointestinal disorders, neurological diseases, and neurodegenerative disorders. Thus, maintaining a healthy intestinal barrier function is essential to sustain health. Probiotics are known for their ability to protect and restore intestinal permeability in vitro and in vivo. The multi-strain probiotics are more efficient than that of a single strain in terms of their protective efficacy. Therefore, the present study was planned and implemented
to study the supplementation of probiotic mix (Lactobacillus paracasei HII01, Bifidobacterium breve, and Bifidobacterium longum) on intestinal permeability, lipid profile, obesity index and metabolic biomarkers in elderly Thai subjects. The results revealed that the supplementation of studied probiotics improved the intestinal barrier function (up to 48%), significantly increasing the high-density lipoprotein (HDL)-cholesterol. Moreover, the intervention improved obesity-related anthropometric
biomarkers and short-chain fatty acid levels in human subjects. The current study strongly
recommends further extended research to confirm the beneficial effect of probiotics, which may pave the way to formulate probiotic-based health supplements to adjuvant the treatment of several metabolic diseases.


Xs: 3.367984 Ys: -0.2272538 Publish year: 2022 keyword: thai__longevity_diet source: Thai title: Prevalence and Associated Factors of Successful Ageing among People 50 Years and Older in a National Community Sample in Thailand abstract: The aim of the study was to assess the prevalence and associated factors of successful ageing (SA) among people 50 years and older in Thailand. We analyzed national cross-sectional data (5092 men and women 50 years or older) from the Health, Aging and Retirement in Thailand (HART) study in 2015. The SA measures included (1) life satisfaction, (2) social engagement, (3) no major illness, (4) no probable depression, and (5) absence of functional disability. The sample included 5092 participants (median age 67 years, interquartile range 60 to 78 years). The prevalence of SA was 60.0% in adults 50 years and older, ranging from 43.8% in Krabi province to 80.2% in Pathum Thani province, 58.1% (≥60 years), and 56.3% (≥65 years), and the prevalence of the components of SA was 92.3% without major illness, 96.1% without functional disability, 87.5% without probable depression, 91.3% social engagement, and 82.3% high life satisfaction. In multivariable Poisson regression analysis, Buddhist religion (adjusted Prevalence Ratio (aPR): 1.50, 95% Confidence Interval (CI): 1.25 to 1.79), high subjective economic status (aPR: 1.29, 95% CI: 1.11 to 1.49), and physical activity (≥150 min/week) (aPR: 1.11, 95% CI: 1.01 to 1.24) were positively associated and increasing age (aPR: 0.993, 95% CI: 0.989 to 0.997) was negatively associated with SA. Almost two in three older adults in Thailand were successfully ageing. Factors associated with SA included being Buddhist, younger age, higher subjective economic status, and higher engagement in physical activity. These identified factors should be incorporated into health promotion intervention programs in Thailand.


Xs: 3.2385087 Ys: 3.849103 Publish year: 2022 keyword: thai__longevity_diet source: Thai title: The Effects of Synbiotics Administration on Stress-Related Parameters in Thai Subjects-A Preliminary Study abstract: Urbanization influences our lifestyle, especially in fast-paced environments where we are more prone to stress. Stress management is considered advantageous in terms of longevity. The use of probiotics for psychological treatment has a small amount of diverse proven evidence to support this. However, studies on stress management in stressed subjects using synbiotics are still limited. The present study aimed to investigate the effects of synbiotics on stress in the Thai population. A total of 32 volunteers were enrolled and screened using a Thai Stress Test (TST) to determine their stress status. Participants were divided into the stressed and the non-stressed groups. Synbiotics preparation comprised a mixture of probiotics strains in a total concentration of 1 × 10 10 CFU/day (5.0 × 10 9 CFU of Lactobacillus paracasei HII01 and 5.0 × 10 9 CFU of Bifidobacterium animalis subsp. lactis) and 10 g prebiotics (5 g galacto-oligosaccharides (GOS), and 5 g oligofructose (FOS)). All parameters were measured at baseline and after the 12th week of the study. In the stressed group, the administration of synbiotics significantly (p < 0.05) reduced the negative scale scores of TST, and tryptophan. In the non-stressed group, the synbiotics administration decreased tryptophan significantly (p < 0.05), whereas dehydroepiandrosterone sulfate (DHEA-S), tumor necrosis factor-α (TNF-α), 5-hydroxyindoleacetic acid (5-HIAA), and short-chain fatty acids (SCFAs), acetate and propio-nate were increased significantly (p < 0.05). In both groups, cortisol, and lipopolysaccharide (LPS) were reduced, whereas anti-inflammatory mediator interleukin-10 (IL-10) and immunoglobulin A (IgA) levels were increased. In conclusion, synbiotics administration attenuated the negative feelings via the negative scale scores of TST in stressed participants by modulating the HPA-axis, IL-10, IgA, and LPS. In comparison, synbiotics administration for participants without stress did not benefit stress status but showed remodeling SCFAs components, HPA-axis, and tryptophan catab-olism.


Xs: 7.263306 Ys: 2.264741 Publish year: 2020 keyword: thai__longevity_diet source: Thai title: Nutritional and therapeutic values of Coccinea grandis: A review abstract: Coccinia grandis also known as Ivy Gourd is a nutrient rich fast growing perennial vine plant of Cucurbitaceae family. It is a dioecious, perennial and herbaceous climber or trailing vine with glabrous stems and tuberous roots. Traditionally it is known for its medicinal and nutritional qualities and its all plant parts like roots, leaves and fruits are used in local medicinal purposes like jaundice, diabetes, wound healing, ulcers, stomach ache, skin disease, fever, asthma, cough. It is a wonderful vegetable plant species having various pharmacological properties like analgesic, antipyretic, anti-inflammatory, antimicrobial, antiulcer, antidiabetic, antioxidant, hypoglycemic, hepatoprotective, antimalarial, antidyslipidemic, anticancer, antitussive, mutagenic.


Xs: 4.066693 Ys: 0.2676756 Publish year: 2014 keyword: thai__longevity_diet source: Thai title: Herbal and dietary supplement use in Bangkok: A survey abstract: : People living in Asian countries including Thailand are likely to use herbal and dietary supplements (HDS). However, there is limited evidence of their usage in Thailand. The objectives of this study were to determine (1) the prevalence of HDS usage amongst a general population in Bangkok; (2) patterns of HDS use; (3) reasons why Bangkok residents use HDS.
: This cross-sectional survey recruited 400 Thai people aged 15 years or over at busy bus stops in Bangkok, Thailand, using convenience sampling. Data were collected via an interview regarding demographics, HDS usage and reasons of using HDS. Descriptive statistics, such as frequencies and percentages, were used to analyse the prevalence and the patterns of HDS use.
: The prevalence of HDS usage in the previous 6 months was 52%. The majority of people who took herbs used them to treat illnesses (58%), whereas the majority of people who took dietary supplements used them to promote well-being (65%). Respondents reported using HDS due to their efficacy (28%), wanting to try them (26%) and safety concerns with conventional medicines (15%).
: Health care providers should be aware of HDS use amongst Thai residents in Bangkok. Policy makers should educate people about appropriate HDS use.


Xs: 2.3073523 Ys: 0.91868716 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Prolonged Honeymoon Period in a Thai Patient With Adult-Onset Type 1 Diabetes Mellitus - Metabolic Flexibility in Autoimmune Diabetes? abstract: Background: ‘Honeymoon’ period among people with type 1 diabetes mellitus (T1DM) refers to the period of time (mostly less than 1 year) which beta-cell is still able to produce insulin to maintain good glycemic control shortly following the development of diabetes. This phenomenon remained incompletely understood but previous studies showed that absence of diabetic ketoacidosis (DKA) at initial presentation, short duration of symptoms, older age at presentation, and strenuous exercise could be potential factors. Herein, we report a 24-year old Thai patient with T1DM who has been in sustained complete remission for more than 5 years while he is maintaining low carbohydrate intake and regular exercise.
Clinical Case: A 24-year-old male presented with a 6-month history of polyuria, polydipsia and weight loss of 15 kilograms (baseline BMI at 27.8 kg/m2). His initial laboratory data showed plasma glucose 398 mg/dL and A1C 9.3%. No ketonemia was found. He was diagnosed with stage 3 of Type 1 DM based on clinical presentation and positive pancreatic auto-antibodies (anti-GAD and anti-IA2). Euthyroid Hashimoto’s thyroiditis was also diagnosed based on his enlarged thyroid gland and positive thyroid auto-antibodies. He was started on basal-bolus insulin regimen for only 2 month and then A1C reversed to 5.9% within 2 months. Insulin was gradually withdrawn and completely stopped. Mixed meal stimulation test (MMST) was firstly evaluated at the second year of his diagnosis. The result revealed stimulated C-peptide at 5.5 ng/dL. Next-generation sequencing panel for monogenic diabetes revealed negative results. The patient maintains healthy lifestyle habit with low carbohydrate intake and regular exercise 5–6 times per week. His body weight was maintained at 60–63 kilograms during the past 4 years. His A1C was maintained between 5.0 to 6.0% without any anti-diabetic medication for more than 5 years. Repeated MMST in every 6–12 months still revealed preserved beta-cell functions and normal stimulated plasma glucose. Interestingly, repeated pancreatic auto-antibodies at 3 years after diagnosis showed negative anti-GAD and anti-IA2, but positive anti-ZnT8. The patient was advised to maintain his bodyweight and healthy behavior together with closely regular OPD follow-up.
Conclusion: Restored beta-cell function with completely insulin withdrawal in new-onset T1DM has been reported in very few cases which have some common factors as in our patient (low carbohydrate intake with regular exercise). Delaying autoimmune activity by reducing metabolic load in newly diagnosed T1DM might play a role in maintaining a honeymoon period and could lead to an innovative therapeutic option in new-onset T1DM.


Xs: 3.367715 Ys: 0.9362644 Publish year: 2018 keyword: thai__longevity_diet source: Thai title: Age-Related Reference Intervals for Blood Amino Acids in Thai Pediatric Population Measured by Liquid Chromatography Tandem Mass Spectrometry abstract: Background
Age, race, and analytic method influence levels of blood amino acids, of which reference intervals are required for the diagnosis and management of inherited metabolic disorders.

Objectives
To establish age-specific reference intervals for blood amino acids in Thai pediatric population measured by liquid chromatography tandem mass spectrometry (LC-MS/MS).

Methods
A cross-sectional study of 277 healthy children from birth to 12 years was conducted. Anthropometric, clinical, and dietary information were recorded. Dried blood spots on a filtered paper were used for measurement by derivatized LC-MS/MS. Factors that might affect amino acids such as fasting time and dietary intake were analyzed using quantile regression analysis.

Results
Levels of thirteen blood amino acids were reported as median and interval from 2.5th–97.5th percentiles. Compared with those of Caucasian, most blood amino acid levels of Thai children were higher. Compared with a previous study using HPLC in Thai children, many amino acid levels are different. Glycine, alanine, leucine/isoleucine, and glutamic acid sharply decreased after birth. Citrulline, arginine, and methionine stayed low from birth throughout childhood, whereas phenylalanine was at middle level and slightly increased during preadolescence.

Conclusion
Reference intervals of age-specific blood amino acids using LC-MS/MS were established in the Thai pediatric population. They diverge from previous studies, substantiating the recommendation that, for the optimal clinical practice, age-specific reference intervals of amino acids should be designated for the particular population and analysis method.


Xs: 4.4046626 Ys: -0.5899496 Publish year: 2018 keyword: thai__longevity_diet source: Thai title: Viewpoint: A Contributory Role of Shell Ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) for Human Longevity in Okinawa, Japan? abstract: The longevity of the population in the Okinawa Islands of Japan has been ascribed to genetic factors and the traditional Okinawa cuisine, which is low in calories and high in plant content. This diet includes shell ginger (Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm) of the ginger family (Zingiberaceae). Due to its local popularity, Alpinia zerumbet has become the subject of a good deal of study at the University of the Ryukyus in Okinawa. Personal local experience and review of the literature now suggest that culinary shell ginger may contribute to longevity among the population in Okinawa. This is supported by its abundant phytochemical content, with antioxidant and anti-obesity properties. The major bioactive phytochemicals are dihydro-5,6-dehydrokawain (DDK; 80–410 mg g−1 fresh weight), 5,6-dehydrokawain (DK; ≤100 mg g−1), and essential oils, phenols, phenolic acids, and fatty acids (≤150 mg g−1 each). Further, Alpinia zerumbet extends the lifespan in animals by 22.6%. In conclusion, culinary shell ginger may significantly contribute to human longevity in Okinawa.


Xs: 2.9268615 Ys: 4.0181646 Publish year: 2020 keyword: thai__longevity_diet source: Thai title: Gut microbiota and old age: Modulating factors and interventions for healthy longevity abstract: Our gut microbiota is a complex and dynamic ecosystem with a paramount role in shaping our metabolic and immunological functions. Recent research suggests that aging may negatively affect the composition, diversity, and function of our microbiota mainly due to alterations in diet and immunologic reactivity (i.e. immunosenescence), and increased incidence of certain diseases and, therefore, increased exposure to certain medication (e.g. antibiotics, proton pump inhibitors). In turn, this aging-related gut dysbiosis may contribute to the initiation and/or progress of other metabolic diseases, and consequently, to a decrease in healthy longevity. On the positive side, promising therapeutic interventions, such as diet supplementation with prebiotics, probiotics and synbiotics, or fecal microbiota transplantation, aimed to counteract these aging-related deleterious consequences, could improve our health, and extend our healthy lifespan. In this context, the current review aims to assess the latest progress in identifying the key elements affecting the gut microbiota of the older adults and their mechanism of action, and the effectiveness of the therapeutic interventions aimed at restoring the diversity and healthy functions of the gut microbiota in older individuals.


Xs: 6.070535 Ys: -1.0898836 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Edible Mushroom Protein Content and Antioxidant Capacity Increase the Longevity of Anastrepha ludens Fruit Flies abstract: This study aimed to determine the effect of the protein and antioxidant contents of edible mushrooms on the longevity of the fruit fly (Anastrepha ludens). The contents of protein (Bradford assay), antioxidants (DPPH and ABTS assays), total phenols, and flavonoids in nine strains of different edible mushroom species were determined. Freeze-dried and finely ground complete mushroom fruiting bodies were used to feed the flies, with a concentration of 0.5% in the diet. Male and female fruit flies, both fertile and sterile, were used in this study. Two controls were used: the standard fly diet and a diet supplemented with cinnamon as a food rich in antioxidants. Differences in protein and antioxidant contents were found among the evaluated strains. Differences were also observed in the responses of female and male flies as well as between the responses of fertile and sterile flies. Overall, the sterile flies lived longer. The addition of mushrooms in the diet resulted in greater longevity than in the controls. The use of sterile flies allowed observation of the effect of proteins and antioxidants on reproduction and the subsequent effect of reproduction on longevity


Xs: 6.5087867 Ys: -0.90394104 Publish year: 2020 keyword: thai__longevity_diet source: Thai title: Biology and predatory ability of the reduviidSycanus falleniStal (Heteroptera: Reduviidae: Harpactorinae) fed on four different preys in laboratory conditions abstract: The reduviid Sycanus falleni Stal (Heteroptera: Reduviidae) is an important predatory insect in biological control pests in vegetable, soybean, corn and rice plants. It is omnivorous species and has a wide range of prey. The influence of fed on four different preys as Pieris rapae (Linnaeus), Spodoptera litura (Fabricius), Plutela xylostella (Linnaeus) and Corcyra cephalonica (Stainton) on biological parameters, ability to eat prey and body weight of the nymph and adult of S. falleni were evaluated in laboratory conditions (26 ± 2 °C, 75 ± 5% RH and light:dark 14:10 h) in Vietnam. The biological parameters of reduviid S. falleni reared on the laboratory were determined by observing the development stage of egg, development stage of nymph, pre-oviposition period, life cycle, longevity of adult, number of eggs laid, sex ratio. The nymph and adults of reduviid S. falleni consumption the number of P. xylostella, P. rapae, S. litura and C. cephalonica larvae were different, and an adult female consumed more than an adult male while the body weight of the I and V nymphal instars, male and female adults of reduviid S. falleni wasn't significantly different (P < 0.01).


Xs: 3.3451512 Ys: -0.068854466 Publish year: 2016 keyword: thai__longevity_diet source: Thai title: Gains in Life Expectancy due to Eliminating Major Causes of Death in Thai Older Persons abstract: Background: The age structure of the population of Thailand has been rapidly changing. The proportion of older persons aged 60 years and over is significantly increasing as a result of a range of declining mortality and, most importantly, decrease in fertility. Burden of disease measured by non-communicable diseases in older persons is at the most elevated key factor when compared with other population groups. This study estimated the gains of life expectancy from elimination of three major causes of death including cerebrovascular disease, heart disease and cancer in older Thai people by gender. Methods: Based on data on causes of death in 2007 from the Bureau of Policy and Strategy, Ministry of Public Health, Thailand, the multiple decrement and cause eliminated life tables were carried out for life expectancy estimates. By eliminating certain causes of death, a more accurate life expectancy, that is capable of predicting gender difference in life expectancy at age 60, is obtained. Results: This study showed that the net gain in life expectancy at age 60 would be 1.2, 1.5 and 4.8 years from heart disease, cerebrovascular disease and cancer, respectively. Men are expected to gain longer life expectancy than women subsequent to elimination of cerebrovascular disease. Women are expected to gain longer life expectancy as a result of elimination of cancer. Conclusion: This study outlined how each of three diseases could affect the life expectancy of Thai older persons. Gains in life expectancy depend on particular causes of death and sex. Therefore, the findings provide potentially relevant evidence for the Thai government to provide improvement of public health policies for older persons to reduce their loss of life, particularly as caused by cerebrovascular disease and cancer. ï¿½ 2016, College of Public Health Sciences. All rights reserved.


Xs: 3.4834466 Ys: 1.7129712 Publish year: 2013 keyword: thai__longevity_diet source: Thai title: Effect of Daily Egg Ingestion with Thai Food on Serum Lipids in Hyperlipidemic Adults abstract: Thai food is one of the healthiest foods. In fact, several Thai dishes, such as Tom Yum soup, are currently under scientific study for their incredible health benefits. Limited data are available on the effects of egg consumption with Thai food in hyperlipidemic patients. To assess the effects of daily egg consumption with Thai food, which is known as low fat diet, on serum lipids profiles in hyperlipidemic subjects without medication treatment, the randomized crossover trial of 71 hyperlipidemic adults (8 men, 63 women) were randomly to one of the two sequences of one and three eggs/day for 4 weeks. Each treatment was separated by a four-week washout period (egg-free). Our data indicated that one or three eggs/day consumption were significantly increases total serum cholesterol ( and versus mg/dL) and LDL-C levels ( and versus mg/dL) as compared to egg-free period. No significant change of serum TG, HDL-C, TC/HDL-C, and LDL-C/HDL-C levels was observed after 1 or 3 eggs consumption daily in this study.


Xs: 3.4287875 Ys: 4.0571933 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: Lactic acid bacteria profiles associated to Thai traditional fermented foods abstract: Probiotics are health promoting gut microbiota which has been used in commercial products to extend its benefits for supporting the gut function and immunity. Besides these, probiotics contribute to reducing blood cholesterol, diabetics, coronary heart disease, and allergic symptoms as well as improving mood along with cognitive activities, reducing skin aging, and promoting longevity. Probiotics aid in promoting longevity as a function of antioxidant activity which allows it to be a potential source of supplement. These factors open an interesting prospect of screening well known probiotics community containing higher antioxidant activity from various Thai local fermented foods. This study aimed to screen targeted lactic acid bacteria (LAB) from 15 plant and animal based Thai local fermented foods by CaCO 3 containing MRS agar and analyzed its antioxidant and probiotic properties. It was found that all 11 isolates considered as potential LAB as it had shown clear zone on CaCO 3 containing MRS agar, exhibited over 70% inhibition of DPPH in both supernatant and pellet. But only one isolate from plant based fermented food showed potential probiotic properties, including acid-bile tolerance, hydrophobicity, and antimicrobial activity, and it was the one that had the highest antioxidant activity. This isolated strain might be further analyzed and developed as a potential longevity promoting supplement.
Vol.9, No.2 pages 35-52 Research Article


Xs: 4.61264 Ys: 1.5087513 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: Associations among Dietary Zinc Intake, Serum Zinc Level and Multiple Comorbidities in Older Adults abstract: Zinc is one of the essential micronutrients in the geriatric population, but the importance of zinc status and dietary zinc intake has been poorly characterized. We aimed to explore the relationships among dietary zinc intake, serum zinc concentrations and multimorbidity in a cross-sectional study of 300 employees of Electric Generating Authority of Thailand aged ≥ 60 years. Comprehensive questionnaires were completed, and clinical and laboratory assessments were performed. Factors associated with low serum zinc concentrations were identified using multivariate multinomial logistic regression analyses. The mean serum zinc level was 80.5 (12.8) µg/dL. After adjustment for baseline characteristics, being female and having been in education for ≤12 years were independent risk factors for the lowest tertile (T1) of serum zinc. After additional adjustment for clinical and biochemical parameters, there was a significant association between depression (Thai Geriatric Depression Scale-15 score > 5) and low serum zinc levels (T1 vs. T3, odds ratio (OR): 2.24; 95% confidence interval (CI): 1.06–4.77). Furthermore, as serum albumin increased, serum zinc concentration substantially increased (T1 vs. T3, OR: 0.01; 95% CI: 0.002–0.070). Therefore, the early detection of risk factors and the further management of depression and low serum albumin may assist physicians in preventing low serum concentrations.


Xs: 7.7273393 Ys: 2.0033064 Publish year: 2015 keyword: thai__longevity_diet source: Thai title: The effectiveness of a standardized rose hip powder, containing seeds and shells of Rosa canina, on cell longevity, skin wrinkles, moisture, and elasticity abstract: Objective
To evaluate the effects of a rose hip powder (Hyben Vital®) made from seeds and shells on cell senescence, skin wrinkling, and aging.

Methods
A total of 34 healthy subjects, aged 35–65 years, with wrinkles on the face (crow’s-feet) were subjected to a randomized and double-blinded clinical study of the effects of the rose hip powder, as compared to astaxanthin, a well-known remedy against wrinkles. During the 8-week study, half of the participants ingested the standardized rose hip product, while the other half ingested astaxanthin. Objective measurements of facial wrinkles, skin moisture, and elasticity were made by using Visioscan, Corneometer, and Cutometer at the beginning of the study, after 4 weeks, and after 8 weeks. Evaluation of participant satisfaction of both supplements was assessed using questionnaires. In addition, the effect of the rose hip preparation on cell longevity was measured in terms of leakage of hemoglobin through red cell membranes (hemolytic index) in blood samples kept in a blood bank for 5 weeks. Significance of all values was attained with P≤0.05.

Results
In the double-blinded study, the rose hip group showed statistically significant improvements in crow’s-feet wrinkles (P<0.05), skin moisture (P<0.05), and elasticity (P<0.05) after 8 weeks of treatment. A similar improvement was observed for astaxanthin, with P-values 0.05, 0.001, and 0.05. Likewise, both groups expressed equal satisfaction with the results obtained in their self-assessment. The rose hip powder further resulted in increased cell longevity of erythrocyte cells during storage for 5 weeks in a blood bank.

Conclusion
Results suggest that intake of the standardized rose hip powder (Hyben Vital®) improves aging-induced skin conditions. The apparent stabilizing effects of the rose hip product on cell membranes of stored erythrocyte cells observed in this study may contribute to improve the cell longevity and obstructing skin aging.


Xs: 6.0758924 Ys: 1.78387 Publish year: 2013 keyword: thai__longevity_diet source: Thai title: Moringa oleifera Mitigates Memory Impairment and Neurodegeneration in Animal Model of Age-Related Dementia abstract: To date, the preventive strategy against dementia is still essential due to the rapid growth of its prevalence and the limited therapeutic efficacy. Based on the crucial role of oxidative stress in age-related dementia and the antioxidant and nootropic activities of Moringa oleifera, the enhancement of spatial memory and neuroprotection of M. oleifera leaves extract in animal model of age-related dementia was determined. The possible underlying mechanism was also investigated. Male Wistar rats, weighing 180-220 g, were orally given M. oleifera leaves extract at doses of 100, 200, and 400 mg/kg at a period of 7 days before and 7 days after the intracerebroventricular administration of AF64A bilaterally. Then, they were assessed memory, neuron density, MDA level, and the activities of SOD, CAT, GSH-Px, and AChE in hippocampus. The results showed that the extract improved spatial memory and neurodegeneration in CA1, CA2, CA3, and dentate gyrus of hippocampus together with the decreased MDA level and AChE activity but increased SOD and CAT activities. Therefore, our data suggest that M. oleifera leaves extract is the potential cognitive enhancer and neuroprotectant. The possible mechanism might occur partly via the decreased oxidative stress and the enhanced cholinergic function. However, further explorations concerning active ingredient(s) are still required.


Xs: 3.7055817 Ys: 0.20099045 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Nutrition label experience and consumption of transitional foods among a nationwide cohort of 42,750 Thai adults abstract: Purpose

The purpose of this paper is to assess the usefulness of nutrition labels in Thailand during nutrition transition from traditional to modern diets that increase salt, sugar, and calorie intake and to note socio-demographic interactions and associations with consumption of transitional processed foods.

Design/methodology/approach

The authors studied 42,750 distance learning Open University adults aged 23-96 years in 2013 residing nationwide and participating in an ongoing community-based prospective cohort study. The authors used multivariable logistic regression to relate nutrition label experiences (“read”, “good understand”, “frequent use”), socio-demographic factors, and consumption of four transitional foods. These foods included “unhealthy” instant foods, carbonated soft drinks, and sweet drinks, or “healthy” milk.

Findings

Overall, two-thirds reported good understanding and frequent use of nutrition labels. Unhealthy transition-indicator processed foods were frequently consumed: instant foods (7 per cent), (carbonated) soft drinks (15 per cent), and sweet drinks (41 per cent). Frequent users of nutrition labels (e.g. females, older persons, professionals) were less likely to consume unhealthy indicator foods. Those with the most positive overall nutrition label experience (“read” + “good understanding” + “frequent use”) had the best indicator food profiles: instant foods (odds ratio (OR) 0.63; 95%CI, 0.56-0.70); soft drinks (OR 0.56; 95%CI, 0.52-0.61); sweet drinks (OR 0.79; 95%CI, 0.74-0.85); milk (OR 1.87; 95%CI, 1.74-2.00).

Originality/value

Knowledge protected – those with most nutrition label experience were least likely to consume unhealthy foods. Results support government regulated nutrition labels, expanding to include sweet drinks. The study is remarkable for its large size and nationwide footprint. Study subjects were educated, represent Thais of the future, and show high awareness of transition-indicator foods.


Xs: 5.396669 Ys: -0.19387886 Publish year: 2019 keyword: thai__longevity_diet source: Thai title: Slow loris density in a fragmented, disturbed dry forest, north-east Thailand abstract: Primate survival in disturbed forests can be governed by a complex of forest variables. For nocturnal arboreal primates, determining these ecological features is notoriously difficult but is critically important for their conservation. Here we assessed the effects of forest type, food availability, human disturbance, and forest structure on the nocturnal Bengal slow loris (Nycticebus bengalensis) in Sakaerat Biosphere, north‐east Thailand, a small disturbed fragment containing dry evergreen, dry dipterocarp, and plantation forests. Distance sampling revealed plantation forest had the highest density estimate (27 loris/km²) followed by dry evergreen forest (17 loris/km²), while dry dipterocarp forest only had four detections. Based on forest type selection analyses, loris had a positive association with sap and fruit‐flower productivity which was highest in plantation forest compared to the natural dry evergreen or dry dipterocarp forests. Furthermore, forest structure selection analysis indicated loris preferred denser canopies. Loris presence was positively associated with canopy height, canopy connections, tree trunk vegetation cover, and canopy density. The higher loris density found in the plantations, as also reported by other studies, was associated with dense vegetation structure and higher food productivity, particularly sap. However, the important structural features found in the plantation forest are strongly dependent on forest maturity, and the reduced longevity of such exotic tree species may limit the conservation importance of plantation forest, merely acting as a short‐term alternative to natural habitat.


Xs: 6.0685096 Ys: -0.64253867 Publish year: 2019 keyword: thai__longevity_diet source: Thai title: Comparative pesticide exposure to Apis mellifera via honey bee-collected pollen in agricultural and non-agricultural areas of Northern Thailand abstract: Pollen is a known route of pesticide exposure in bees, and pollen diversity and quality are necessary for optimal honey bee development and longevity. Here, the nutritional richness of protein for bees based on pollen/plant diversity and the pesticide residues in pollen were studied. Honey bee colonies (Apis mellifera L.) were used to collect pollen at monthly intervals in four provinces (Chiang Mai, Lampang, Phayao and Phrae) of Northern Thailand. One agricultural and one non-agricultural site in four provinces were selected for a total of eight distinct sites. Bee-collected pollen was sorted by color and identified to family using light microscopy to estimate plant diversity at each location. Gramineae and Asteraceae were the most common pollen types collected by honey bees in eight locations in northern Thailand. The two sites in Chiang Mai province consistently showed ample plant diversity as six or more pollen types were recorded on dates of collection. In general, Phayao had the lowest pollen diversity in both agricultural and non-agricultural sites with only 1–3 pollen types collected in each area. Plantaginaceae was only found in March-April in the agricultural area of Phrae province. Moreover, we found eight different pesticides such as herbicides, fungicides, formamidines, organophosphates, pyrethroids and neonicotinoids at different levels in agricultural area but only four pesticides were detected in non-agricultural locations. Overall the detection of agricultural chemicals was low relative to other studies in Europe and North America. Therefore, many areas of Northern Thailand do offer a relatively clean environment in which to keep honey bees and produce honey.


Xs: 6.5997515 Ys: 2.7753265 Publish year: 2002 keyword: thai__longevity_diet source: Thai title: Changes in β‐Carotene and Vitamin A Contents of Vitamin A‐rich Foods in Thailand During Preservation and Storage abstract: To prolong consumption of β-carotene and vitamin A-rich foods in Thailand during off-season, plant foods such as ripe mango, ripe papaya, pumpkin, Pak Sien (a local Thai vegetable), and Chinese green cabbage were preserved by candying and pickling. Chicken liver was incorporated into local rice-flour chips. Pumpkin was also stored as fresh whole fruit at room temperature. β-Carotene loss in candied mango and papaya during processing was 17 to 18%, and loss continued from 30 to 40% during storage over 3 months. In contrast, β- carotene contents increased during fermentation of pickled Pak Sien and Chinese green cabbage, ranging from 30 to 40%. A 3-month storage of fresh whole pumpkin in the shade led to as much as a 1263% increase of β-carotene concentrations. On the other hand, vitamin A content was reduced about 50% during the processing of fried chicken liver chips and continued to lose 16% more during storage.


Xs: 2.9380383 Ys: 0.2935551 Publish year: 2018 keyword: thai__longevity_diet source: Thai title: Prevalence of Diabetes and Relationship with Socioeconomic Status in the Thai Population: National Health Examination Survey, 2004–2014 abstract: Objective
To determine the prevalence and trend of diabetes, related glycemic control, and influential socioeconomic (SES) factors in the Thai population aged ≥20 years during 2004–2014.

Methods
Data from the Thai National Health Examination Survey 2004, 2009, and 2014 were used. Age-adjusted prevalence was calculated, and the associations of education levels with prevalence of diabetes and glycemic control were examined using logistic regression.

Results
Age-adjusted prevalence of diabetes increased from 7.7% in 2004 to 7.8% in 2009 and 9.9% in 2014 (8.9% among men and 10.8% among women). Proportions of undiagnosed diabetes were slightly decreased but remained high in 2014 (51.2% for men and 41.3% for women). Diabetes prevalence was higher among those with primary education in both sexes; however, undiagnosed diabetes was higher among women with secondary and university educations. The percentages of those treated and controlled slightly improved among men (45.9%) but not among women (36.4%). Unmet glycemic control was also higher among women with secondary education levels and among men with university-level educations.

Conclusions
Epidemic diabetes continues to grow in the Thai population, particularly in individuals with lower educational attainment. Measures to detect new cases and strengthen glycemic control should be scaled up.


Xs: 6.3517632 Ys: -1.1386671 Publish year: 2011 keyword: thai__longevity_diet source: Thai title: Male Mating History and Body Size Influence Female Fecundity and Longevity of the Dengue Vector Aedes aegypti abstract: Male reproductive success is dependent on insemination success and reproductive output. During mating, male mosquitoes transfer not just sperm, but also seminal fluid proteins that may have profound effects on mated female biology and behavior. In this study, we investigated the role of male body size and mating history on semen depletion, female longevity, and reproductive success in Aedes aegypti L. Small and large males were mated in rapid succession with up to five females. Our results indicate that large males had greater mating capacity than small males. A reduction in fecundity by >50% was observed in females that were fourth to mate with small males in comparison with females that mated earlier in sequence. For females mated to large males, this reduction became evident for females that mated fifth in sequence. No loss of fertility (measured as hatch rate) was observed in females that were third-fifth in mating sequence compared with females mated to virgin males. When females were maintained on a low-quality (5% sucrose) diet, those mated to virgin males had a greater longevity compared with females mated third in sequence. We conclude that small males experience more rapid seminal depletion than large males, and discuss the role of semen depletion in the mated female. Our results contribute toward a better understanding of the complexity of Ae. aegypti mating biology and provide refined estimates of mating capacity for genetic control efforts.


Xs: 4.8208704 Ys: -1.5370294 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: Longevity through diet restriction and immunity abstract: The share of the population that is aging is growing rapidly. In an aging society, technologies and interventions that delay the aging process are of great interest. Dietary restriction (DR) is the most reproducible and effective nutritional intervention tested to date for delaying the aging process and prolonging the health span in animal models. Preventive effects of DR on age-related diseases have also been reported in human. In addition, highly conserved signaling pathways from small animal models to human mediate the effects of DR. Recent evidence has shown that the immune system is closely related to the effects of DR, and functions as a major mechanism of DR in healthy aging. This review discusses the effects of DR in delaying aging and preventing age-related diseases in animal, including human, and introduces the molecular mechanisms that mediate these effects. In addition, it reports scientific findings on the relationship between the immune system and DRinduced longevity. The review highlights the role of immunity as a potential mediator of the effects of DR on longevity, and provides insights into healthy aging in human.


Xs: 4.504236 Ys: 1.1242876 Publish year: 2024 keyword: thai__longevity_diet source: Thai title: Occurrence, distribution, and ecological risk assessment of heavy metals in Chao Phraya River, Thailand abstract: Understanding heavy metals in rivers is crucial, as their presence and distribution impact water quality, ecosystem health, and human well-being. This study examined the presence and levels of nine heavy metals (Cd, Cr, Cu, Fe, Hg, Mn, Ni, Pb, and Zn) in 16 surface water samples along the Chao Phraya River, identifying Fe, Mn, Zn, and Cr as predominant metals. Although average concentrations in both rainy and dry seasons generally adhered to WHO guidelines, Mn exceeded these limits yet remained within Thailand’s acceptable standards. Seasonal variations were observed in the Chao Phraya River, and Spearman’s correlation coefficient analysis established significant associations between season and concentrations of heavy metals. The water quality index (WQI) demonstrated varied water quality statuses at each sampling point along the Chao Phraya River, indicating poor conditions during the rainy season, further deteriorating to very poor conditions in the dry season. The hazard potential index (HPI) was employed to assess heavy metal contamination, revealing that during the dry season in the estuary area, the HPI value exceeded the critical threshold index, indicating the presence of heavy metal pollution in the water and unsuitable for consumption. Using the species sensitivity distribution model, an ecological risk assessment ranked the heavy metals’ HC5 values as Pb > Zn > Cr > Cu > Hg > Cd > Ni, identifying nickel as the most detrimental and lead as the least toxic. Despite Cr and Zn showing a moderate risk, and Cu and Ni posing a high risk to aquatic organisms, the main contributors to ecological risk were identified as Cu, Ni, and Zn, suggesting a significant potential ecological risk in the Chao Phraya River’s surface water. The results of this study provide fundamental insights that can direct future actions in preventing and managing heavy metal pollution in the river ecosystem.


Xs: 5.424083 Ys: -1.0504756 Publish year: 2019 keyword: thai__longevity_diet source: Thai title: Leaf extract of Caesalpinia mimosoides enhances oxidative stress resistance and prolongs lifespan in Caenorhabditis elegans abstract: Background:
Caesalpinia mimosoides, a vegetable consumed in Thailand, has been reported to exhibit in vitro antioxidant properties. The in vivo antioxidant and anti-aging activities have not been investigated. The aim of this research was to study the antioxidant activity of C. mimosoides extracts in Caenorhabditis elegans, a widely used model organism in this context.

Methods:
C. elegans were treated with C. mimosoides extracts in a various concentrations. To investigate the protective effects of the extract against oxidative stress, wild-type N2 were used to determine survival rate under oxidative stress and intracellular ROS. To study underlying mechanisms, the mutant strains with GFP reporter gene including TJ356, CF1553, EU1 and LD4 were used to study DAF-16, SOD-3, SKN-1 and GST-4 gene, respectively. Lifespan and aging pigment of the worms were also investigated.

Results:
A leaf extract of C. mimosoides improved resistance to oxidative stress and reduced intracellular ROS accumulation in nematodes. The antioxidant effects were mediated through the DAF-16/FOXO pathway and SOD-3 expression, whereas the expression of SKN-1 and GST-4 were not altered. The extract also prolonged lifespan and decreased aging pigments, while the body length and brood size of the worms were not affected by the extract, indicating low toxicity and excluding dietary restriction.

Conclusions:
The results of this study establish the antioxidant activity of C. mimosoides extract in vivo and suggest its potential as a dietary supplement and alternative medicine to defend against oxidative stress and aging, which should be investigated in intervention studies.


Xs: 7.846244 Ys: 2.09518 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: Anti-aging of phenolic-rich Acanthus ebracteatus Vahl. extracts abstract: Background
Sea holly has long been used in traditional Thai medicine for longevity, skin inflammation, skin dullness and as a treatment for itchy skin. The white flower cultivar Acanthus ebracteatus Vahl. has been documented to perform better remedies than the purple flower A. ilicifolius. Nonetheless, preparation of the phenolic-rich extract of A. ebracteatus, including safety and cellular assessments relevant for inflammation and aging treatment is sparingly presented. In this study, the extracts of A. ebracteatus were prepared and comparatively quantified on total phenolic contents. In vitro activities by means of ABTS, DPPH, FRAP and mushroom tyrosinase inhibitory assays were undertaken. The extracts were UPLC analyzed and examined on cellular safety and activities.

Results
The phenolic-rich extracts of A. ebracteatus were prepared and standardized in verbascoside. The extracts were noted to have in vitro antioxidant and anti-tyrosinase activities. Cellular activities, co-cultures and ex vivo human skin appointed for cutaneous aging treatment, i.e., photoaging, are promising including antioxidant, anti-melanogenesis, anti-inflammatory (IL-6 and IL-8), anti-MMP and collagen production stimulating as well as anti-senescence activities.

Conclusions
Sea holly is highlighted as a potential source for beneficial cutaneous phenolics, especially verbascoside. The extracts were proven to be safe and efficient for cutaneous aging treatment indicated by their antioxidant, anti-melanogenesis, collagen stimulating, anti-inflame and anti-senescence activities. The plant extracts are therefore appointed for use as innovative agents for anti-aging purposes.

Graphical Abstract


Xs: 3.0369432 Ys: 0.6374251 Publish year: 2005 keyword: thai__longevity_diet source: Thai title: Prevalence of dyslipidemia in rural Thai adults: An epidemiologic study in Khon Kaen province abstract: Dyslipidemia is an important, modifiable CHD risk factor. Previous studies have reported the prevalence of dyslipidemia particularly in urban populations. However, its prevalence in rural Northeast Thailand has not been well documented since extensive dietary and lifestyle transitions induced by the rapid socio-economic development of the late 1990s and early 2000s. The authors, therefore, conducted a cross-sectional assessment for the prevalence of dyslipidemia among rural Thais (in Khon Kaen province) using the National Cholesterol Education Program (NCEP) Adult Treatment Panel (ATP III) Guidelines. The 325 subjects recruited (136 men; 189 women) averaged 53.8 +/- 17.6 years of age (range, 20-88). After having the subjects fast 12 hours, serum samples were collected. Total cholesterol, triglycerides, low-density lipoprotein (LDL-C) and high-density lipoprotein (HDL-C) cholesterols were measured. The prevalence of hypercholesterolemia (> 200 mg/dL), hypertriglyceridemia (> 150 mg/dL), high LDL-C (> 130 mg/dL) and low HDL-C (< 40 mg/dL) was 31, 40, 20 and 14 per cent, respectively. Women had a 2- to 3.5-fold higher prevalence of hypercholesterolemia and high LDL-C than men, while the prevalence of hypertriglyceridemia was comparable. The prevalence of dyslipidemia increased with advancing age and increasing BMI; notwithstanding, a high prevalence of dyslipidemia was observed in the youngest tertile as well. In conclusion, the present study demonstrated a high prevalence of dyslipidemia in rural Thai adults; consequently, primary lipid screening should be considered for all ages.


Xs: 6.3194494 Ys: -1.0154301 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Larval diet affects development and reproduction of East Asian strain of the fall armyworm, Spodoptera frugiperda abstract: In December 11, 2018, the fall armyworm (FAW), Spodoptera frugiperda invaded China and has since impacted local maize, sorghum and other crops. Here, we draw on laboratory experiments to show how different host crops (i.e., maize, sorghum, wheat and rice) and artificial diet affect larval growth and adult reproduction of one local FAW strain. Larval diet affected development duration, pupation rate, survival and emergence rate of pupae, and S. frugiperda adult fecundity. FAW attained the slowest larval development (19.4 days) on sorghum and the fastest (14.1 days) on artificial diet, with larvae attaining 99.6% survival on the latter food item. On rice, FAW larvae attained survival rate of 0.4% and were unable to pupate successfully. Pupation rate and pupal survival varied substantially between artificial diet and live plantlets at different phenological stages. Pupal weight was the highest (0.26 g) on artificial diet and the lowest (0.14 g) on sorghum, while FAW females reached the highest fecundity (699.7 eggs/female) on 2-leaf stage maize. Egg hatching rate equaled 93.6% on 4- or 5-leaf stage maize and 36.6% on artificial diet. FAW intrinsic rate of natural increase and the finite rate of increase varied between larval diets, reflecting how young maize leaves are the most suitable diet. Our findings can help to refine laboratory rearing protocols, devise population forecasting models or guide the deployment of ‘area-wide’ integrated pest management (IPM) modules in FAW-invaded areas of China and other Asian countries.


Xs: 4.665207 Ys: 1.328516 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Health impact assessment of arsenic and cadmium intake via rice consumption in Bangkok, Thailand abstract: Consumption of contaminated food is a major route of exposure to toxic contaminants for humans. To protect against potential negative health effects from rice consumption, As and Cd concentrations in rice sold in Bangkok were determined, and non-carcinogenic and carcinogenic risk assessments were conducted. Four types of rice (n = 97), namely, white jasmine, white, glutinous, and brown jasmine, were collected. Samples were acid-digested and analyzed for total concentrations of As and Cd by ICP-MS. The average concentrations of As and Cd were 0.205 ± 0.008 and 0.019 ± 0.001 mg kg⁻¹, respectively. Approximately 22.8, 62.5, and 57.1% of white, white jasmine, and brown jasmine rice, respectively, contained As concentrations exceeding the Codex inorganic As standards for polished and unpolished rice. Brown jasmine rice contained significantly higher As concentrations than the other types of rice. However, Cd concentrations in all rice samples were significantly lower than the Codex standard of 0.4 mg kg⁻¹. Children are exposed to the highest amounts of both elements. Concerning As exposure through the consumption of different types of rice in the same age group, the consumption of brown jasmine rice caused approximately 1.7 to 2.3 times higher As exposure rates compared to the consumption of other types of rice. Non-carcinogenic risks (hazard quotient (HQ)) of As exposure from all types of rice were higher than the threshold limit of 1. HQ in children ranging from 2.1 to 4.9 was significantly higher than HQ in the other age groups. The cancer risks from As exposure were negligible in all groups.


Xs: 2.6318798 Ys: 0.0338482 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Psychometric Properties of Diabetes Management Self-Efficacy in Thai Type 2 Diabetes Mellitus Patients: A Multicenter Study abstract: Objective
The aims of this study were to translate and psychometrically evaluate the Thai version of diabetes management self-efficacy scale (T-DMSES) and to examine its association with HbA1c control in diabetic individuals.

Methods
This study recruited patients from outpatient diabetes clinics of both community and university hospitals. The first phases of this study involved translation of the existing DMSES into Thai, and in the second phase, we evaluated its psychometric properties. The construct validity was evaluated using confirmatory factor analysis. Criterion validity of DMSES was subsequently evaluated by examining DMSES's association with HbA1c control.

Results
The T-DMSES contains 20 items across four factors. Confirmatory factor analysis demonstrated the construct validity of T-DMSES (χ² = 645.142, df = 164, p < 0.001, CFI = 0.98, RMSEA = 0.065, TLI = 0.977, and AGFI = 0.981). The T-DMSES was also shown to be criterion valid with most subscales highly associated with HbA1c control.

Conclusion
The T-DMSES was shown to have good psychometric properties. It is likely to provide valuable insights into the epidemiology of diabetes management self-efficacy and may also prove useful in evaluating interventions for raising diabetes management self-efficacy, which in turn, improve both patient self-management and blood sugar control.


Xs: 4.1859293 Ys: 0.3491126 Publish year: 2020 keyword: thai__longevity_diet source: Thai title: Potential factors that influence usage of complementary and alternative medicine worldwide: a systematic review abstract: Objectives
To determine similarities and differences in the reasons for using or not using complementary and alternative medicine (CAM) amongst general and condition-specific populations, and amongst populations in each region of the globe.

Methods
A literature search was performed on Pubmed, ScienceDirect and EMBASE. Keywords: ‘herbal medicine’ OR ‘herbal and dietary supplement’ OR ‘complementary and alternative medicine’ AND ‘reason’ OR ‘attitude’. Quantitative or qualitative original articles in English, published between 2003 and 2018 were reviewed. Conference proceedings, pilot studies, protocols, letters, and reviews were excluded. Papers were appraised using valid tools and a ‘risk of bias’ assessment was also performed. Thematic analysis was conducted. Reasons were coded in each paper, then codes were grouped into categories. If several categories reported similar reasons, these were combined into a theme. Themes were then analysed using χ ² tests to identify the main factors related to reasons for CAM usage.

Results
231 publications were included. Reasons for CAM use amongst general and condition-specific populations were similar. The top three reasons for CAM use were: (1) having an expectation of benefits of CAM (84% of publications), (2) dissatisfaction with conventional medicine (37%) and (3) the perceived safety of CAM (37%). Internal health locus of control as an influencing factor was more likely to be reported in Western populations, whereas the social networks was a common factor amongst Asian populations ( p < 0.05). Affordability, easy access to CAM and tradition were significant factors amongst African populations ( p < 0.05). Negative attitudes towards CAM and satisfaction with conventional medicine (CM) were the main reasons for non-use ( p < 0.05).

Conclusions
Dissatisfaction with CM and positive attitudes toward CAM, motivate people to use CAM. In contrast, satisfaction with CM and negative attitudes towards CAM are the main reasons for non-use.


Xs: 4.654295 Ys: 0.5189754 Publish year: 2004 keyword: thai__longevity_diet source: Thai title: Trade-offs in Ecosystem-scale Optimization of Fisheries Management Policies abstract: Recent applications of ecosystem models have had some apparent success evaluating how fisheries and environmental changes have affected marine populations, and a stage has been reached where ecosystem models can be used to describe agents of mortality and trophic interdependencies in the marine environment with some credibility. This success has raised the stakes for modeling and caused its focus to evolve to include ecosystem-scale optimization policies aimed, modestly, at determining the mix of fishing fleets that will optimize a combination of objectives, subject to the assumptions inherent in the model—as is the case with all models. A resemblance between our model predictions and real-world conditions may indicate that trade-offs among economic, social, and ecosystem objectives resulting from optimization for fleet configurations are more pronounced than hitherto recognized. The present paper reports the consequences of such optimizations for a model meant to mimic aspects of the Gulf of Thailand ecosystem, intended to determine how the model reacts to different weightings for the objective functions individually and jointly to examine the trade-offs involved. The results indicate that optimizing for economic profit is consistent with including ecosystem considerations, whereas optimizing landed value is in conflict with profit as well as ecosystem optimization.


Xs: 4.9041767 Ys: -0.6250469 Publish year: 2004 keyword: thai__longevity_diet source: Thai title: Sow Longevity abstract: Poor sow longevity in commercial pork production systems can lead to economic inefficiency and animal well being concerns. The quest by commercial pork producers to provide consumers with lean pork and improve production efficiency through increasing kilograms of lean sold per sow per year and decreasing the amount of feed that it takes to produce a kilogram of pork is likely to have led to the decrease in productive lifetime of breeding herd females in most commercial pig herds. The emphasis on these traits has resulted in a decreased emphasis on maintaining productivity throughout a sow's lifetime. Improving sow longevity would improve a pork producer's profitability by reducing replacement gilt expenses and associated development, isolation, and acclimation costs. We report here a summary of sow longevity and culling studies to date. These studies focus on the economics of sow longevity and the reasons sows are removed from the breeding herd, as well as genetic, nutritional, gilt development, and other factors that contribute to sow longevity. These studies clearly point out that sow longevity is a complex trait with many factors that can contribute to a sow having a long and productive life in a commercial breeding herd. This review shows that additional research is needed with modern commercial maternal lines that will investigate everything from identifying individual genes to management, gilt development, nutrition, and a whole host of factors that contribute to improved sow longevity. Identifying factors that influence the longevity of modern maternal lines along with genetic improvement of the trait could assist many commercial pork producers in becoming more efficient.


Xs: 5.137788 Ys: 1.8797953 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Neuroprotective and Cognitive-Enhancing Effects of Microencapsulation of Mulberry Fruit Extract in Animal Model of Menopausal Women with Metabolic Syndrome abstract: Currently, the neuroprotectant and memory-enhancing agent for menopausal women with metabolic syndrome is required. Based on the advantages of polyphenolics on numerous changes observed in menopause with metabolic syndrome and the encapsulation method, we hypothesized that microencapsulated mulberry fruit extract (MME) could protect brain damage and improve memory impairment in an animal model of menopause with metabolic syndrome. To test this hypothesis, MME at doses of 10, 50, and 250 mg/kg was given to female Wistar rats which were induced experimental menopause with metabolic syndrome by bilateral ovariectomy (OVX) and fed with high-carbohydrate high-fat (HCHF) diet for 8 weeks. Spatial memory together with neuron density, oxidative stress status, acetylcholinesterase, and phosphorylation of Erk in the hippocampus was assessed at the end of the study. It was found that MME decreased memory impairment, oxidative stress status, and AChE activity but increased neuron density and Erk phosphorylation in the hippocampus. Therefore, the neuroprotective and memory-enhancing effects of MME might partly involve the enhanced cholinergic function and Erk phosphorylation but decreased oxidative stress status in hippocampus. Therefore, MME is the potential novel neuroprotectant and memory-enhancing agent for menopause with metabolic syndrome. However, further research especially clinical trial is still necessary.


Xs: 4.993277 Ys: -1.2016344 Publish year: 2022 keyword: thai__longevity_diet source: Thai title: Pharmaceutical and nutraceutical activation of FOXO3 for healthy longevity abstract: Life expectancy has increased substantially over the last 150 years. Yet this means that now most people also spend a greater length of time suffering from various age-associated diseases. As such, delaying age-related functional decline and extending healthspan, the period of active older years free from disease and disability, is an overarching objective of current aging research. Geroprotectors, compounds that target pathways that causally influence aging, are increasingly recognized as a means to extend healthspan in the aging population. Meanwhile, FOXO3 has emerged as a geroprotective gene intricately involved in aging and healthspan. FOXO3 genetic variants are linked to human longevity, reduced disease risks, and even self-reported health. Therefore, identification of FOXO3-activating compounds represents one of the most direct candidate approaches to extending healthspan in aging humans. In this work, we review compounds that activate FOXO3, or influence healthspan or lifespan in a FOXO3-dependent manner. These compounds can be classified as pharmaceuticals, including PI3K/AKT inhibitors and AMPK activators, antidepressants and antipsychotics, muscle relaxants, and HDAC inhibitors, or as nutraceuticals, including primary metabolites involved in cell growth and sustenance, and secondary metabolites including extracts, polyphenols, terpenoids, and other purified natural compounds. The compounds documented here provide a basis and resource for further research and development, with the ultimate goal of promoting healthy longevity in humans.


Xs: 4.596089 Ys: -1.4063573 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: Fasting and dietary restriction impact on immune system in aging population: a narrative review abstract: Dietary habits and nutrition metabolism are strongly associated with human physiology. Overnutrition or calorie excess has been shown to have many deleterious effects. At the same time, the impact of fasting as part of dietary restriction (DR) remains elusive, especially on the immune system during the aging process. Here, we describe current updates of fasting and DR impact on the immune system and host responses in the aging population. Generally, fasting causes alteration in immune cell distribution by increasing the homing of peripheral cells to the bone marrow. In the aging population, fasting reduces the inflammatory response and promotes cell regeneration. Additionally, fasting is associated with the B cell clonal expansions important to counter infection. This review offers new perspectives and enhances our understanding of immunosenescence as a key to healthy aging.


Xs: 3.3836052 Ys: -0.00062607246 Publish year: 2009 keyword: thai__longevity_diet source: Thai title: Ways of healthy aging: A case study of elderly people in a Northern Thai village abstract: This ethnographic study was conducted to explore ways of healthy aging and the influence of culture on health-related behaviors in a rural community in Northern Thailand. In-depth interviews, focus group discussions, participant observations and field notes were used to understand the lives of seven healthy Thai older adults aged 75 years and over. Data were collected from March 2007 to February 2008, with ongoing ethnographic analysis involving coding, identifying patterns, generalizing and making reflective notes to elucidate the cultural patterns of behavior. All informants perceived health as interrelated with their life styles, which was, in turn, closely related to their cultural roots, suggesting that culture influences the health of all members of smaller, closely knit communities, including the elderly, by integrating physical, social and spiritual health for older adults and their families.


Xs: 5.0190964 Ys: 2.3445594 Publish year: 2020 keyword: thai__longevity_diet source: Thai title: Phytosome Loading the Combined Extract of Mulberry Fruit and Ginger Protects against Cerebral Ischemia in Metabolic Syndrome Rats abstract: The prevalence of ischemic stroke in metabolic syndrome (MetS) is continually increasing and produces a great impact on both qualities of life and annual healthcare budget. Due to the efficiency limitation of the current therapeutic strategy, the poor availability of polyphenol substances induced by the first pass effect and the beneficial effects of mulberry fruit and ginger on brain and MetS-related diseases together with the synergistic concept, the neuroprotective effect against ischemic stroke in MetS condition of phytosome containing the combined extract of mulberry fruit and ginger (PMG) has been considered. To explore the neuroprotective effect and possible underlying mechanism of PMG on brain damage in cerebral ischemic rat with MetS, male Wistar rats were induced MetS by high-carbohydrate high-fat diet (HCHF) for 16 weeks and subjected to the cerebral ischemia/reperfusion injury (CIRI) at the right middle cerebral artery (Rt. MCAO). PMG at doses of 50, 100, and 200 mg/kg were orally fed with for 21 days, and they were assessed brain damage, neurological deficit score, and the changes of oxidative stress markers, inflammatory markers, PPARγ expression, and epigenetic modification via DNMT-1 were performed. All doses of PMG significantly improved brain infarction, brain edema, and neurological deficit score. In addition, the reduction in DNMT-1, MDA level, NF-κB, TNFα, and C-reactive protein together with the increase in SOD, CAT, and GPH-Px activities, and PPARγ expression in the lesion brain were also observed. The current data clearly revealed the neuroprotective effect against cerebral ischemia with MetS condition. The possible underlying mechanism might occur partly via the suppression of DNMT-1 giving rise to the improvement of signal transduction via PPARγ resulting in the decreasing of inflammation and oxidative stress. In conclusion, PMG is the potential neuroprotectant candidate against ischemic stroke in the MetS condition. However, the clinical trial is still essential.

1. Introduction
Currently, stroke and metabolic syndrome (MetS) have been recognized as important health problems worldwide due to the increasing prevalence and the great impact on healthcare budget [1–3]. It has been demonstrated that MetS increases the risk of stroke [4–6] via the increase in intracranial atherosclerosis [7]. In addition, it can also increase oxidative stress and inflammation [8], the important factors playing the pivotal roles on the pathophysiology of ischemic stroke, and may increase severity of stroke [9]. Despite the increasing prevalence and importance of stroke with MetS, the therapeutic efficacy is not in the satisfaction level.
Recently, it has been demonstrated that the substance possessing antioxidant and anti-inflammation such as the combined extract of black stick rice and dill significantly improves brain damage and deficits in an animal model of ischemic stroke in MetS condition [10, 11]. Our previous study also clearly demonstrates that the phytosome containing the combined extract of ginger rhizome and mulberry fruit (PMG) can also decrease oxidative stress and inflammation [12]. This raises the possibility that PMG which also possesses the aforementioned activities [13–17] can also protect against ischemic stroke in MetS condition. Currently, no data concerning the aforementioned effect are available. Therefore, this study was set up to determine the neuroprotective effect against ischemic stroke in the rat model of MetS induced by a high carbohydrate high fat (HCHF) diet. In addition, the possible underlying mechanism especially the roles of oxidative stress, inflammation, PPARγ signal transduction, and epigenetic mechanism modification were also determined.

2. Materials and Methods

2.1. Preparation of PMG
The authentication of ginger rhizomes (Zingiber officinale Roscoe) which were harvested from Khon Kaen province, Thailand, was performed by the expert in pharmacognosy of the National Museum of THAI Traditional Medicine, Thailand and the voucher specimen No. 0002402 was deposited at the National Museum of THAI Traditional Medicine. Ripen mulberry fruit (Morus alba Linn. var. Chiangmai) used in this study was identified and kindly provided by the Queen Sirikit Department of Sericulture Center (Udon Thani province), Ministry of Agriculture and Cooperatives, Thailand, and the voucher specimen 61001 was deposited at Research Institute of Human High Performance and Health Promotion, Khon Kaen University, Khon Kaen, Thailand. The phytosome loading with the combined extract of ginger rhizome extract and ripen mulberry fruit was prepared as prepared according to the method of Palachai and coworkers [12]. In brief, 50% and 95% hydroalcoholic extract of mulberry fruit and ginger were prepared by using the maceration method. Then, the combined extract at a ratio of 1 : 1 was mixed and encapsulated with phosphatidylcholine matrix in order to produce phytosome containing the combined extract of mulberry fruit and ginger (PMG). The concentrations of active ingredients including total phenolic compounds, flavonoids, gingerol, cyanidin-3-O-glucoside, quercetin-3-rutinoside, ferulic acid, and gallic acid in PMG were as same as those mentioned in our previous study [12].

2.2. Experimental Protocol
The experimental animals in this study were male Wistar rats, weighting 180-220 g (8 weeks old), from National Laboratory Animal Center, Salaya, Nakhon Pathom, Thailand. The animals were kept under standard laboratory conditions at and 12 : 12 hours light-dark cycle. They were provided food and water ad libitum and housed in standard metal cages (6 per cage) and allowed to accustom to the laboratory condition for one week. All procedures and experimental protocols were approved by the Institutional Animal Ethics Committee of Khon Kaen University (record no. IACUC-KKU 95/60). After the acclimatization, all animals were randomly divided into 8 groups. (a)Group I:Normal diet (ND) + vehicle: the animals in this group were provided a normal diet and treated with vehicle(b)Group II:HCHF + Sham + vehicle: MetS rats induced by high-carbohydrate high-fat (HCHF) diet were orally given vehicle 21 days before and 14 days after exposing to sham operation(c)Group III:HCHF + MCAO + vehicle: MetS rats induced by HCHF diet as mentioned in (b) were orally given vehicle 21 days before and 14 days after exposing to the occlusion of the right middle cerebral artery (Rt. MCAO).(d)Group IV: HCHF + MCAO + vitamin C: MetS rats induced by HCHF diet and received vitamin C at a dose of 250 mg/kg BW 21 days before and 14 days after exposing to Rt. MCAO(e)Group V: HCHF + MCAO + Piracetam: MetS rats induced by HCHF diet and received piracetam at a dose of 250 mg/kg BW 21 days before and 14 days after exposing to Rt. MCAO(f)Group VI-VIII: HCHF + MCAO +PMG: MetS rats induced by HCHF diet and received PMG at various doses ranging from 50, 100, and 200 mg/kg BW 21 days before and 14 days after exposing to Rt. MCAO
The normal diet used in this study contained 4.5% fat, 42% carbohydrate, and 24% protein whereas the HCHF diet contained 35% fat, 45% carbohydrate, and 20% protein. After the exposure to a 16-week-feeding period, rats which showed the full criteria of MetS as mentioned in the previous study [12] were recruited for further study. The recruited animals were randomly assigned to various treatments as mentioned earlier. Food, water intake, and body weight changes were recorded every week. Then, 21 days after treatment with the assigned substances, the MetS rats were subjected to the occlusion of the right middle cerebral artery and continually treated with the assigned substances for 14 days after Rt. MCAO induction. The neurological deficit scores were assessed at 24 hours after Rt. MCAO and every 7 days throughout the study period while brain infarction volume, brain edema, the determinations C-reactive protein in serum were determined at 24 hours after Rt. MCAO. The determination of oxidative stress markers including malondialdehyde (MDA), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH-Px), and the expressions of DNA-methyltransferase 1 (DNMT-1), peroxisome proliferator-activated receptor-gamma (PPARγ), nuclear factor kappa B (NF-κB), and tumor necrosis factor-alpha (TNFα) in the lesioned brain were performed at the end of the study. The experimental protocol was summarized in Figure 1.

(a)


Xs: 5.31847 Ys: -0.6845637 Publish year: 2020 keyword: thai__longevity_diet source: Thai title: Plant-Derived Bioactives and Oxidative Stress-Related Disorders: A Key Trend towards Healthy Aging and Longevity Promotion abstract: Plants and their corresponding botanical preparations have been used for centuries due to their remarkable potential in both the treatment and prevention of oxidative stress-related disorders. Aging and aging-related diseases, like cardiovascular disease, cancer, diabetes, and neurodegenerative disorders, which have increased exponentially, are intrinsically related with redox imbalance and oxidative stress. Hundreds of biologically active constituents are present in each whole plant matrix, providing promissory bioactive effects for human beings. Indeed, the worldwide population has devoted increased attention and preference for the use of medicinal plants for healthy aging and longevity promotion. In fact, plant-derived bioactives present a broad spectrum of biological effects, and their antioxidant, anti-inflammatory, and, more recently, anti-aging effects, are considered to be a hot topic among the medical and scientific communities. Nonetheless, despite the numerous biological effects, it should not be forgotten that some bioactive molecules are prone to oxidation and can even exert pro-oxidant effects. In this sense, the objective of the present review is to provide a detailed overview of plant-derived bioactives in age-related disorders. Specifically, the role of phytochemicals as antioxidants and pro-oxidant agents is carefully addressed, as is their therapeutic relevance in longevity, aging-related disorders, and healthy-aging promotion. Finally, an eye-opening look into the overall evidence of plant compounds related to longevity is presented.


Xs: 2.818382 Ys: 4.153411 Publish year: 2015 keyword: thai__longevity_diet source: Thai title: Comparative analysis of gut microbiota in elderly people of urbanized towns and longevity villages abstract: To understand differences in the gut microbiota between elderly people of urbanized town communities (UTC) and longevity village communities (LVC), we analyzed fecal microbiota collected from individuals living in 2 UTC (Seoul and Chuncheon) and 3 LVC (Gurye, Damyang, and Soonchang) selected on the basis of indices for superlongevity (the ratio of centenarians to the total population) and longevity (the ratio of those aged 85 years or greater to those aged 65 years or greater) in South Korea by 454 pyrosequencing.
Taxonomy-based analysis showed that The relative abundance of Firmicutes, Tenericutes, and Actinobacteria was significantly lower in LVC than in UTC. Due to an increase of Firmicutes and a reduction of Bacteroidetes, the ratio of Firmicutes to Bacteroidetes in the gut microbiota was greater in UTC adults than in UTC children or LVC adults. The population levels of Bacteroides, Prevotella, and Lachnospira were significantly higher in LVC than in UTC, but the levels of Dialister, Subdoligranulum, Megamonas, EF401882_g, and AM275436_g were lower in LVC than in UTC. Although most of the species detected in LVC were detected in UTC, some Bacteroides spp. and Faecalibacterium spp. were detected only in LVC. Among Bacteroides spp., ACWH_s, EF403317_s, and EF403722_s were detected in children and LVC samples only but FJ363527_s, 4P000677_s, and 4P000015_s were detected in UTC samples. EF402172_s and EF404388_s, members of Faecalibacterium spp., which are known to have anti-inflammatory properties, were detected in LVC and children only (>3.9% of total sequence). In addition, the fecal lipopolysaccharides (LPS) content was significantly higher in UTC than in LVC.
These findings suggest that maintaining gut microbiota, including Faecalibacterium spp. EF402172_s and EF404388_s, as well as low LPS levels may play an important role in preserving residents' health in LVC.


Xs: 4.7773285 Ys: 1.9348422 Publish year: 2009 keyword: thai__longevity_diet source: Thai title: Serum concentration and dietary intake of vitamins A and E in low-income South African elderly abstract: Adequate dietary intake of antioxidants is vital for the promotion of health, well being and longevity of the elderly. This study assessed the prevalence of vitamin A (retinol) and vitamin E (alpha-tocopherol) deficiency in a population of low-income South African elderly.
Serum vitamin A and vitamin E concentrations were determined in 235 persons aged 60-93 years in Sharpeville, South Africa. Dietary assessment was done using 24-h recall. Weight and height were measured to determine body mass index.
The mean and standard deviation of serum levels in the elderly were 1.41+/-1.4 micromol/L for vitamin A and 2.1+/-1.1 mg/l for vitamin E. The proportion with deficient serum vitamin A was 28.2% and 26.5% for men and women respectively and 20.5% and 20.9% respectively for deficient vitamin E concentrations. Almost one-third of the subjects consumed less than 100% of the Estimated Average Requirement for both vitamins. Mean vitamin A intake was 426+/-666 microg in men and 368+/-811 microg in women, mean vitamin E intake for men and women was 5.4+/-5.2 microg and 4.0+/-0.5 mg respectively. The predominant macronutrient consumed was carbohydrate. No relationship existed between biochemical and dietary intake parameters of vitamins A and E.
These findings indicate poor dietary intake and high prevalence of vitamins A and E deficiency among this elderly population. Sustainable community-based interventions are needed to address this nutritional vulnerability in this community.


Xs: 6.491071 Ys: -1.1174381 Publish year: 2013 keyword: thai__longevity_diet source: Thai title: Efficiency of Three Diets for Larval Development in Mass Rearing Aedes albopictus (Diptera: Culicidae) abstract: A fundamental step in establishing a mass production system is the development of a larval diet that promotes high adult performance at a reasonable cost. To identify a suitable larval diet for Aedes albopictus (Skuse), three diets were compared: a standard laboratory diet used at the Centro Agricoltura Ambiente, Italy (CAA) and two diets developed specifically for mosquito mass rearing at the FAO/IAEA Laboratory, Austria. The two IAEA diets, without affecting survival to the pupal stage, resulted in a shorter time to pupation and to emergence when compared with the CAA diet. At 24 h from pupation onset, 50 and 90% of the male pupae produced on the CAA and IAEA diets, respectively, had formed and could be collected. The diet received during the larval stage affected the longevity of adult males with access to water only, with best results observed when using the CAA larval diet. However, similar longevity among diet treatments was observed when males were supplied with sucrose solution. No differences were observed in the effects of larval diet on adult male size or female fecundity and fertility. Considering these results, along with the relative costs of the three diets, the IAEA 2 diet is found to be the preferred choice for mass rearing of Aedes albopictus, particularly if a sugar meal can be given to adult males before release, to ensure their teneral reserves are sufficient for survival, dispersal, and mating in the field.


Xs: 6.264081 Ys: -0.65392554 Publish year: 2009 keyword: thai__longevity_diet source: Thai title: The pollination ecology of durian ( Durio zibethinus, Bombacaceae) in southern Thailand abstract: The floral biology and pollination ecology of durian, Durio zibethinus, were determined in eight semi-wild trees in mixed-fruit orchards in southern Thailand during April-May 2003 and 2005. Flowers open fully at 16h00–16h30 and most androecia drop around 01h00. Anthers dehisce at 19h30–20h00 when the stigmata are already receptive. In a series of pollination experiments, fruit was set in all treatments within 10 d. The greatest pollination success occurred after hand-crossed (76.6%), open (54.4%) and emasculation pollination (53.3%). Consistently, hand-crossed (12.2%), emasculation (8.7%) and open pollination (5.1%) yielded a substantial fruit set 2 mo after the pollination experiments. Very low pollination success in facilitated autogamy suggests that most durian trees are highly self incompatible. No mature fruit was found after insect pollination and automatic autogamy. Fruit bats, especially Eonycteris spelaea, are the major pollinators of this durian although the giant honey bee (Apis dorsata) was the most frequent visitor to the flowers. Bats visited durian flowers at the rate of 26.1 (SD = 20.7) visits per inflorescence per night. Since this semi-wild durian depends on fruit bats as its pollinator, protecting fruit bat populations and their roosts is vital for the production of the durian fruit crop.