Xs: 3.432393 Ys: -0.0037852898 Publish year: 2006 keyword: thai__longevity_diet source: Thai title: Ageing, lifestyle modifications, and cardiovascular disease in developing countries abstract: Developing countries face the double menace of still prevalent infectious diseases and increasing cardiovascular disease (CVD) with epidemic proportions in the near future, linked to demographic changes (expansion and ageing), and to urbanisation and lifestyle modifications. It is estimated that the elderly population will increase globally (over 80% during the next 25 years), with a large share of this rise in the developing world because of expanding populations. Increasing longevity prolongs the time exposure to risk factors, resulting in a greater probability of CVD. As a paradox, increased longevity due to improved social and economical conditions associated with lifestyle changes in the direction of a rich diet and sedentary habits in the last century, is one of the main contributors to the incremental trend in CVD. The variable increase rate of CVD in different nations may reflect different stages of "epidemiological transition" and it is probable that the relatively slow changes seen in developing populations through the epidemiological transition may occur at an accelerated pace in individuals migrating from nations in need to affluent societies (i.e. Hispanics to the USA, Africans to Europe). Because of restrained economic conditions in the developing world, the greatest gains in controlling the CVD epidemic lies in its prevention. Healthy foods should be widely available and affordable, and healthy dietary practices such as increased consumption of fresh fruits and vegetables, reduced consumption of saturated fat, salt, and simple sugars, may be promoted in all populations. Specific strategies for smoking and overweight control may be regulation of marketed tobacco and unhealthy fast food and promotion of an active lifestyle. Greater longevity and economic progress are accompanied by an increasing burden of CVD and other chronic diseases with an important decrease in quality of life, which should question the benefit of these additional years without quality.


Xs: 4.660153 Ys: 1.0962718 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Microplastics Contamination in Commercial Green Mussels from Selected Wet Markets in Thailand abstract: Mussels have been identified as sentinel organisms (around the world) that indicate microplastic (MP) pollution. Since they are filter feeders, they easily uptake MPs. Mussels sold in commercial markets have been identified as an ideal way to directly quantify human exposure to MPs through seafood consumption. There are no studies reported on MP contamination of market-sold species in Thailand. This study investigates the level of MP contamination in market-sold green mussels, which is a popular seafood in Thailand. A total of 90 green mussels (Perna viridis) collected from three markets were analyzed for the number, polymer types, and morphology of the MPs. Fourier-Transform Infrared Micro-Spectroscopy (micro-FTIR) analysis was used for polymer identification. Nile Red (NR) tagging was used for the enumeration of MPs. MPs were widely discovered in green mussels from all three markets with 100% detection frequency. The average abundance of MPs in green mussels was quantified as 7.32 ± 8.33 items/mussel and 1.53 ± 2.04 items/g (wet weight). Ethylene/propylene copolymer followed by low-density polyethylene (PE-LD), polypropylene (PP), and polyethylene terephthalate (PET) were found. Fragments (75.4%) were the most common morphotype, followed by fibers (24.6%). Results indicate that the consumption of green mussels as a food can be one of the exposure pathways for the Thai population. Moreover, smaller size MPs were predominant, which are reported to cause higher impacts.


Xs: 5.0167255 Ys: -1.6825848 Publish year: 2014 keyword: thai__longevity_diet source: Thai title: Altered dietary methionine differentially impacts glutathione and methionine metabolism in long-living growth hormone-deficient Ames dwarf and wild-type mice abstract: Background
Extending mammalian health span and life span has been achieved under a variety of dietary restriction protocols. Reducing the intake of a specific amino acid has also been shown to extend health and longevity. We recently reported that methionine (MET) restriction is not effective in life span extension in growth hormone (GH) signaling mutants. To better understand the apparent necessity of GH in the 'sensing' of altered dietary MET, the current study was designed to evaluate MET and glutathione (GSH) metabolism (as well as other pathways) in long-living GH-deficient Ames dwarf and wild-type mice following 8 weeks of restricted (0.16%), low (0.43%), or enriched (1.3%) dietary MET consumption. Metabolite expression was examined in liver tissue, while gene and protein expression were evaluated in liver, kidney, and muscle tissues.

Results
Body weight was maintained in dwarf mice on the MET diets, while wild-type mice on higher levels of MET gained weight. Liver MET levels were similar in Ames mice, while several MET pathway enzymes were elevated regardless of dietary MET intake. Transsulfuration enzymes were also elevated in Ames mice but differences in cysteine levels were not different between genotypes. Dwarf mice maintained higher levels of GSH on MET restriction compared to wild-type mice, while genotype and diet effects were also detected in thioredoxin and glutaredoxin. MET restriction increased transmethylation in both genotypes as indicated by increased S-adenosylmethionine (SAM), betaine, and dimethylglycine. Diet did not impact levels of glycolytic components, but dwarf mice exhibited higher levels of key members of this pathway. Coenzyme A and measures of fatty acid oxidation were elevated in dwarf mice and unaffected by diet.

Conclusions
This component analysis between Ames and wild-type mice suggests that the life span differences observed may result from the atypical MET metabolism and downstream effects on multiple systems. The overall lack of responsiveness to the different diets is well reflected across many metabolic pathways in dwarf mice indicating the importance of GH signaling in the ability to discriminate dietary amino acid levels.


Xs: 3.1316285 Ys: 0.6061245 Publish year: 2006 keyword: thai__longevity_diet source: Thai title: Rural-urban difference in lipid levels and prevalence of dyslipidemia:A population-based study in Khon Kaen Province, Thailand abstract: To determine the lipid levels and examine the effect of an urban lifestyle on dyslipidemia, by comparing the lipid levels and the prevalence of dyslipidemia of rural vs. urban dwellers in Thailand
A cross-sectional study was conducted in both rural and urban areas of Khon Kaen province. After a 12-hour fast, blood was drawn for assessment of total cholesterol (TC), triglyceride (TG), high-density lipoprotein (HDL-C) and low-density lipoprotein (LDL-C) cholesterol. The classification of dyslipidemia was based on the NCEP A TP III guidelines.
The authors recruited 916 subjects (595 urban; 321 rural), ranging between 20 and 88 years of age. In both the men and women, the mean TC and LDL-C were significantly higher in urban vs. rural subjects (TC; 207 vs. 169 for men and 204 vs. 192 mg/dl for women and LDL-C; 120 vs. 87 for men and 122 vs. 110 mg/dl for women, p < 0.001). The rural women had a significantly higher mean TG (159 vs. 111 mg/dl, p < 0.001) but lower HDL-C (51 vs. 59, mg/dl, p < 0.001) than urban women. The TG and HDL-C between urban and rural men was not significantly different. Urban men had a significantly higher prevalence of dyslipidemia (TC > or =240 and LDL-C > or = 60 mg/dl) than rural men (25.9 vs. .3.7 per cent for TC and 16.7 vs. 3.7 percent for LDL-C, p < 0.001) while the prevalence of hypertriglyceridemia (> or =200 mg/dl) and low HDL-C (< 40 mg/dl) was significantly higher in rural women (18.2 vs. 7.9 percent for TG and 15.0 vs. 3.8 per cent of HDL-C, p < 0.001). The results were unchanged after matching for age and sex between the urban and rural populations.
This present study demonstrated a significant difference in urban vs. rural lipid levels and the prevalence of dyslipidemia. Migration to urban centers and adopting an urban lifestyle is likely related to the rising lipid level and prevalence of dyslipidemia.


Xs: 3.6835203 Ys: -0.10339927 Publish year: 2011 keyword: thai__longevity_diet source: Thai title: "Silver" product design: Product innovation for older people abstract: Aging populations challenge companies across different countries and industries to respond to the changing needs, demands and expectations of their growing shares of older customers. This opens room for improving or developing innovations - products as well as services - that correspond to the diverse expectations. New product development for older customers or 'Silver' product design is one way to approach the 'silver' market - without explicitly excluding younger customers. Research in this field is still in its infancy. Silver product design focuses on individual autonomy, representing an elementary aspect of good life, disappearing in a more or less continuous manner over the life cycle of a human being. Offering solutions that will allow people to maintain or recover autonomy and to use products and services in an independent manner therefore seems to be a promising avenue for companies innovating across different industries. The general concept of autonomy can be perceived as a boundary-spanning argument and a common denominator for starting development initiatives leading to innovations targeting the silver market. Cross-case analysis based on four different product innovations addressing typical needs of older people are used to present how firms in different industrial contexts and user-settings address such needs, which have their roots in a need to stay autonomous and independent. Technological, marketing and strategy-related observations as well as communalities and differences of the cases are being discussed and very first implications for managing the front end of silver product development sketched. --


Xs: 6.910514 Ys: 3.1684728 Publish year: 2016 keyword: thai__longevity_diet source: Thai title: Antioxidant-Enhancing Property of the Polar Fraction of Mangosteen Pericarp Extract and Evaluation of Its Safety in Humans abstract: Crude extract from the pericarp of the mangosteen (mangosteen extract [ME]) has exhibited several medicinal properties in both animal models and human cell lines. Interestingly, the cytotoxic activities were always observed in nonpolar fraction of the extract whereas the potent antioxidant was often found in polar fraction. Although it has been demonstrated that the polar fraction of ME exhibited the antioxidant activity, the safety of the polar fraction of ME has never been thoroughly investigated in humans. In this study, we investigated the safety of oral administration of the polar fraction of ME in 11 healthy Thai volunteers. During a 24-week period of the study, only minor and tolerable side effects were reported; no serious side effects were documented. Blood chemistry studies also showed no liver damage or kidney dysfunction in all subjects. We also demonstrated antioxidant property of the polar fraction of ME both in vitro and in vivo . Interestingly, oral administration of the polar fraction of ME enhanced the antioxidant capability of red blood cells and decreased oxidative damage to proteins within red blood cells and whole blood.


Xs: 7.1189604 Ys: 1.665551 Publish year: 2013 keyword: thai__longevity_diet source: Thai title: Overview of botanical status in EU, USA, and Thailand abstract: The botanical status in EU, USA, and Thailand is different owing to the regulatory status, the progress of science, and the influence of culture and society. In the EU, botanicals are positioned as herbal medicinal products and food supplements, in the US they are regulated as dietary supplements but often used as traditional medicines, and in Thailand, they are regulated and used as traditional medicines. Information for some of the most popular botanicals from each country is included in this review.


Xs: 7.9926333 Ys: 2.2920983 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: In Vitro, In Vivo, and In Silico Analyses of Molecular Anti-Pigmentation Mechanisms of Selected Thai Rejuvenating Remedy and Bioactive Metabolites abstract: Thai rejuvenating remedies are mixed herbal formulas promoting longevity. Due to the complexity, the biological activities of these remedies are minimal. Therefore, in this study, the authors evaluated the anti-pigmentation effect at the molecular level of the selected Thai rejuvenating remedy to fulfill the knowledge gap. First, the authors found that the selected remedy showed promising activity against the tyrosinase enzyme with an IC50 value of 9.41 µg/mL. In the comparison, kojic acid (positive control) exhibited an IC50 value of 3.92 µg/mL against the same enzyme. Later, the authors identified glabridin as a bioactive molecule against tyrosinase with an IC50 value of 0.08 µg/mL. However, ethyl p-methoxycinnamate was the most abundant metabolite found in the remedy. The authors also found that the selected remedy and glabridin reduced the melanin content in the cell-based assay (B16F1) but not in the zebrafish larvae experiment. Finally, the authors conducted a computational investigation through molecular docking proposing a theoretical molecular interplay between glabridin, ethyl p-methoxycinnamate, and target proteins (tyrosinase and melanocortin-1 receptor, MC1R). Hence, in this study, the authors reported the molecular anti-pigmentation mechanism of the selected Thai rejuvenating remedy for the first time by combining the results from in silico, in vitro, and in vivo experiments.


Xs: 6.2632103 Ys: -1.2130617 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Survival of the House Fly (Diptera: Muscidae) on Truvia and Other Sweeteners abstract: The house fly, Musca domestica L. (Diptera: Muscidae), is a disease vector of mechanically transmitted pathogens including bacteria, viruses, and protozoans. Opportunities for pathogen transmission can increase as fly longevity increases. Dietary preferences play an important role in insect longevity; therefore, we investigated house fly preferences, sucrose availability, and caloric constraints on house fly longevity. Experimental goals were: 1) to test the effects of calorie restriction on survival of house flies by manipulating concentrations of erythritol (low caloric content) and sucrose (high caloric content), and comparing commercial sweeteners of differing calorie content, 2) to identify house fly preferences for either erythritol or sucrose, and 3) to evaluate the insecticidal activity or toxicity of erythritol on house flies. Our data show that house flies may prefer high calorie options when given a choice and that house fly longevity likely increases as calorie content increases. Additionally, no significant differences in longevity were observed between the water only control (zero calories) and erythritol treatments. This suggests that decreased survival rates and death could be the result of starvation rather than insecticidal activity. This research furthers our understanding of house fly survival and sugar-feeding behavior.


Xs: 6.466286 Ys: -0.90120405 Publish year: 2013 keyword: thai__longevity_diet source: Thai title: OVIPOSITION AND LONGEVITY OF COCCINELLA SP. (COLEOPTERA: COCCINELLIDAE) ON ARTIFICIAL DIETS abstract: Coccinella sp. is a polyphagous predator which is potential to be developed into a biological control agent for aphids. The research was aimed to determine the oviposition and longevity of the adults predators when given artificial diets and various kinds of drinks. The experiment was performed by placing a pair of insect adults into a Petri dish, covered with a piece of filter paper, containing five mg of food made of ground honey bee larvae (Apis cerana) and then given a drink that is stored or absorbed on a sponge or a cotton swab as a treatment. There were nine treatments and each repeated three times. The results showed that significant differences among the treatments were present, both in the number of groups of eggs and the number of individual eggs produced by an adult predator. The highest number of eggs (323.7 eggs) and the number of egg groups (69.3) laid by an adult was found when the adult was presented with the artificial food and drink of sugar solution in the sponge. When the predator was supplied with the artificial food and water in a sponge, the lowest number of individual eggs and groups of eggs were laid, 65.00 eggs and 19.7 egg groups, respectively. Longevity of the female predator was the longest when given a drink of sugar solution compared to the other treatments. For mass-rearing of predator Coccinella sp. on artificial diet, drinks solution made of honey or sugar solution prepared in the sponge should be added.


Xs: 3.6907938 Ys: 0.045454867 Publish year: 2022 keyword: thai__longevity_diet source: Thai title: Attribute Framework Validation for Wellness Tourism within the Context of Thailand abstract: Background: Research on the theoretical integration of attributes of wellness tourism in the form of the physical, mental, spiritual, and environmental (PMSE) attribute framework and the effect of cultural differences on the framework validation has not been conducted before. Objectives: This study developed and validated the key underlying attributes of the wellness tourism experience framework within the Thailand context. Methods: From reviewing the related literature to identify potential sub attributes under the four dimensions of the PMSE framework, themes were developed using a theory- and prior research-driven method within different cultural contexts. The fitness of the PMSE attribute framework model within the context of Thailand wellness tourism was confirmed through a survey design with a quantitative approach from the generalities of the sample groups. The entire dataset was statistically tested with descriptive statistics and confirmatory factor analysis (CFA). Results and Conclusions: After adjustments, the four-factors with a 28-item model substantiated the data. The results validated that the mental experience dimension accounted for the most variance, with an indicator value of 0.99 in the framework, predicting the effective wellness tourism experience better than the other attributes. Experience design should involve the participation of all stakeholders in the wellness tourism system in terms of managerial contribution. Recommendations for the planning of wellness experiences concerning each four-factor will be investigated in future studies.


Xs: 6.194802 Ys: -0.6055754 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Flower-visiting bat species contribute unequally toward agricultural pollination ecosystem services in southern Thailand abstract: The large majority of angiosperm species depend on animals for pollination, including many agricultural crops, and plant-pollinator interactions have been extensively studied. However, not all floral visitors actually transfer pollen, and efforts to distinguish true pollinators from mere visitors are particularly scarce among the bat pollination literature. To determine whether Old World bat species are equally effective pollinators in mixed-agricultural areas of southern Thailand, we examined six night-blooming plant taxa and quantified pollinator importance (PI) of seven common nectarivorous bat species. PI was calculated as the product of nightly bat visitation rate (obtained from mist-netting data) and pollen transfer efficiency (estimated from bat pollen loads). We found that PI varied by both bat species and plant species. In general, the nectar-specialist bat species were more important pollinators, yet their order of importance differed across our focal plant species. In addition, PI was dictated more by pollen transfer effectiveness than visitation rate. Our findings highlight the importance of Old World bat pollinators within southern Thailand's mixed-agricultural landscape and illustrate how seemingly similar floral visitors can have very different contributions toward plant pollination success.


Xs: 6.326524 Ys: -1.1207706 Publish year: 2014 keyword: thai__longevity_diet source: Thai title: Effect of Diet Quality on Survival and Reproduction of Adult Paederus fuscipes (Coleoptera: Staphylinidae) abstract: The survival and reproduction of the beetle Paederus fuscipes Curtis on diets that differed in macronutrient composition were investigated in the laboratory. The sex organs of females fed each test diet were dissected to evaluate the ovarian development over time. Adults fed on a carbohydrate-rich diet lived longer than adults fed the other diets, but this diet provided insufficient nutrients for reproduction. Females fed on a protein-rich diet had high fecundity; however, the mean longevity of reproductive adult P. fuscipes significantly was shortened by 20‐30 d compared with longevity of 60‐70 d for adults fed a carbohydrate-rich diet. In contrast, adults that were provided lipid-rich diet had low survival and fecundity. Overall, the development of previtellogenic follicles was significantly affected by diet regime and days since starting a particular diet. The follicle size of females given protein-rich diet increased 0.5-fold 2 wk after beginning the diet. In contrast, the development of the follicles was slow in females given the carbohydrate-rich diet and the follicles degenerated in females given the lipid-rich diet. In terms of ovarian maturation, females fed on a protein-rich diet contained mostly vitellogenic and chorionated follicles. In contrast, the ovarioles of females on the carbohydrate-rich diet were largely occupied with previtellogenic and vitellogenic follicles, whereas for a lipid-rich diet, the follicles remained at the previtellogenic stage throughout the experiment.


Xs: 5.8294873 Ys: -0.15700907 Publish year: 2011 keyword: thai__longevity_diet source: Thai title: Characterization of venomous snakes of Thailand abstract: Background: Envenoming by snakebite is an important public health problem in rural tropics. Venomous snake families such as Elapidae and Viperidae frequently produce severe poisoning. Anti-venoms are not available for all venomous snakes of Thailand and there is need for more development in this field. Objective: We characterized the important venomous snakes' distribution of Thailand. Method: Venomous snake species are described in details including their identification, range, and extraterritorial distribution. Result: Eighteen snake species of the family Elapidae are summarized in their characteristics and distribution. There are three species of Naja, one species of Ophiophagus, three species of Bungarus, four species of Calliophis, one species of Sinomicrurus, two species of Laticauda, and four species of subfamily Hydrophiinae. Fifteen snake species of the family Viperidae consisting of one species of subfamily Viperinae and fourteen species of subfamily Crotalinae are also discussed. Conclusion: All these snakes are venomous and their venom is potentially fatal since birth.


Xs: 5.3942976 Ys: -1.1270201 Publish year: 2019 keyword: thai__longevity_diet source: Thai title: Antiaging, Stress Resistance, and Neuroprotective Efficacies of Cleistocalyx nervosum var. paniala Fruit Extracts Using Caenorhabditis elegans Model abstract: Plant parts and their bioactive compounds are widely used by mankind for their health benefits. Cleistocalyx nervosum var. paniala is one berry fruit, native to Thailand, known to exhibit various health benefits in vitro . The present study was focused on analyzing the antiaging, stress resistance, and neuroprotective effects of C. nervosum in model system Caenorhabditis elegans using physiological assays, fluorescent imaging, and qPCR analysis. The results suggest that the fruit extract was able to significantly extend the median and maximum lifespan of the nematode. It could also extend the healthspan by reducing the accumulation of the “age pigment” lipofuscin, inside the nematode along with regulating the expression of col-19 , egl-8 , egl-30 , dgk-1 , and goa-1 genes. Further, the extracts upregulated the expression of daf-16 while downregulating the expression of daf-2 and age-1 in wild-type nematodes. Interestingly, it could extend the lifespan in DAF-16 mutants suggesting that the extension of lifespan and healthspan was dependent and independent of DAF-16-mediated pathway. The fruit extract was also observed to reduce the level of Reactive Oxygen Species (ROS) inside the nematode during oxidative stress. The qPCR analysis suggests the involvement of skn-1 and sir-2.1 in initiating stress resistance by activating the antioxidant mechanism. Additionally, the fruit could also elicit neuroprotection as it could extend the median and maximum lifespan of transgenic strain integrated with A β . SKN-1 could play a pivotal role in establishing the antiaging, stress resistance, and neuroprotective effect of C. nervosum. Overall, C. nervosum can be used as a nutraceutical in the food industry which could offer potential health benefits.


Xs: 3.0554163 Ys: 0.089992076 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Knowledge of Stroke Risk Factors and Warning Signs in Patients with Recurrent Stroke or Recurrent Transient Ischaemic Attack in Thailand abstract: Stroke is a global burden. It is not known whether patients who are most at risk of stroke (recurrent stroke or recurrent transient ischaemic attack) have enough knowledge of stroke risk factors and warning signs. The aim of this study was to assess the knowledge of stroke risk factors and warning signs in this high-risk population. We performed a cross-sectional questionnaire-based study of patients with recurrent stroke or recurrent TIA admitted to Srinagarind Hospital and Khon Kaen Hospital, Thailand. A total of 140 patients were included in the study (age 65.6±11.3 years [mean ± SD], 62 females). Using an open-ended questionnaire, nearly one-third of patients (31.4%) could not name any risk factors for stroke. The most commonly recognized risk factors were hypertension (35%), dyslipidemia (28.6%), and diabetes (22.9%). Regarding stroke warning signs, the most commonly recognized warning signs were sudden unilateral weakness (61.4%), sudden trouble with speaking (25.7%), and sudden trouble with walking, loss of balance, or dizziness (21.4%). Nineteen patients (13.6%) could not identify any warning signs. The results showed that knowledge of stroke obtained from open-ended questionnaires is still unsatisfactory. The healthcare provider should provide structured interventions to increase knowledge and awareness of stroke in these patients.


Xs: 3.6219354 Ys: 0.143903 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: PATRON-CLIENT LINKAGES PUBLICATION abstract: Political development of emerging liberal democracies is gauged based on the level of democratic governance. Democratic governance promotes citizens’ participation, transparency and accountability in access to information and use of public resources, responsiveness to citizens’ needs, effectiveness and efficiency in service delivery, equitability in sharing of resources, inclusiveness in decision making and the rule of law. This review paper examined the implication of political patron-client linkages/networks and practices on democratic governance in developing democracies. This review paper relies on the existing secondary data from various parts of the world in providing a conceptual explanation of political patron-client networks/linkages how it impact on democratic governance. This study noted that patron-client networks and practices have profound negative implications for the way in which democracy functions, and the capacity of governments to produce needed public policies and services. It generally reverse the standard accountability relationship, affects the development of the political institutions necessary for democratic development and accountability, leads to politicization of the state administrative bureaucracy, contribute to larger public deficits and public sector inefficiencies, increases cases of corruption and a culture of impunity and make it difficult to punish individuals for corrupt behavior. Patron-client linkage is therefore pervasive to the practice of good governance in the developing democracies and this study recommends for economic liberalization, democratization reforms, decentralization of governance, civil service reform and electoral civic education as mitigative measures.


Xs: 4.484548 Ys: -1.0475752 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: The Longevity Protein Klotho: A Promising Tool to Monitor Lifestyle Improvements abstract: Aging is not a disease; it is a natural evolution of human physiology. Medical advances have extended our life expectancy, but chronic diseases and geriatric syndrome continue to affect the increasingly aging population. Yet modern medicine perpetuates an approach based on treatment rather than prevention and education. In order to help solve this ever-growing problem, a new discipline has emerged: lifestyle medicine. Nutrition, physical activity, stress management, restorative sleep, social connection, and avoidance of risky substances are the pillars on which lifestyle medicine is founded. The aim of this discipline is to increase healthspan and reduce the duration of morbidity by making changes to our lifestyle. In this review, we propose the use of klotho protein as a novel biomarker for lifestyle medicine in order to quantify and monitor the health status of individuals, as no integrative tool currently exists.


Xs: 2.773125 Ys: 4.1608315 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Regional Diets Targeting Gut Microbial Dynamics to Support Prolonged Healthspan abstract: In the last 150 years, we have seen a significant increase in average life expectancy, associated with a shift from infectious to non-communicable diseases. The rising incidence of these diseases, for which age is often the largest risk factor, highlights the need for contemporary societies to improve healthy ageing for their growing silver generations. As ageing is an inevitable, non-reversing and highly individualised process, we need to better understand how non-genetic factors like diet choices and commensal gut microbes can modulate the biology of ageing. In this review, we discuss how geographical and ethnic variations influence habitual dietary patterns, nutrient structure, and gut microbial profiles with potential impact on the human healthspan. Several gut microbial genera have been associated with healthy elderly populations but are highly variable across populations. It seems unlikely that a universal pro-longevity gut microbiome exists. Rather, the optimal microbiome appears to be conditional on the microbial functionality acting on regional- and ethnicity-specific trends driven by cultural food context. We also highlight dietary and microbial factors that have been observed to elicit individual and clustered biological responses. Finally, we identify next generation avenues to modify otherwise fixed host functions and the individual ageing trajectory by manipulating the malleable gut microbiome with regionally adapted, personalised food intervention regimens targeted at prolonging human healthspan.


Xs: 3.901992 Ys: 0.40662414 Publish year: 2007 keyword: thai__longevity_diet source: Thai title: The nutrition transition in high- and low-income countries: What are the policy lessons? abstract: This article examines the speed of changes in diets, activity patterns, and body composition, summarizes major dietary changes, and provides some sense of the way the burden of obesity is shifting from the rich to the poor globally. The focus is on the lower- and middle-income world with some examples from higher-income countries. Then macro policy options are examined. A case study of edible oil pricing in China is presented. The challenge is for the agricultural economics profession to focus on this major global issue-one which challenges some of the earlier paradigms of food policy and agricultural development. Copyright 2007 International Association of Agricultural Economists.


Xs: 4.9557037 Ys: -1.4246286 Publish year: 2018 keyword: thai__longevity_diet source: Thai title: Cellular Senescence in Intervertebral Disc Aging and Degeneration abstract: Purpose of review
Age is a major risk factor for multiple disease pathologies, including chronic back pain, which stems from age-related degenerative changes to intervertebral disc tissue. Growing evidence suggests that the change in phenotype of disc cells to a senescent phenotype may be one of the major driving forces of age-associated disc degeneration. This review discusses the known stressors that promote development of senescence in disc tissue and the underlying molecular mechanisms disc cells adopt to enable their transition to a senescent phenotype.

Recent findings
Increased number of senescent cells has been observed with advancing age and degeneration in disc tissue. Additionally, in vitro studies have confirmed the catabolic nature of stress-induced senescent disc cells. Several factors have been shown to establish senescence via multiple different underlying mechanisms, including the NF-κB, Wnt/B-Catenin, and SIRT1 pathways.

Summary
Cellular senescence can serve as a therapeutic target to combat age-associated disc degeneration. However, whether the different stressors utilizing different signaling networks establish different kinds of senescent types in disc cells is currently unknown and warrants further investigation.


Xs: 6.4358344 Ys: -0.93061686 Publish year: 2010 keyword: thai__longevity_diet source: Thai title: Laboratory studies on control of the maize weevil Sitophilus zeamais by the parasitoid Anisopteromalus calandrae abstract: Anisopteromalus calandrae (Howard), a cosmopolitan parasitoid, attacks several beetle pests of stored products, including the maize weevil, Sitophilus zeamais (Motschulsky). Two laboratory experiments were conducted at ambient conditions (25-29 degrees C, 60-70% RH natural photoperiod). A short-term experiment evaluated the density of A. calandrae (0, 4, 8, 12, 16, or 20 per box) for the optimal production of parasitoids in 3825-cm(3) boxes containing milled rice. The percentage of parasitoid emergence was highest and the percentages of weevil emergence and parasitoid-induced mortality i.e., parasitoid mortality resulting from superparasitism were relatively low with 16 females per box rather than with smaller (0 to 12) or larger (20) numbers of females added per box. The decline in parasitoid emergence at the highest parasitoid density tested (20 females per box) was probably due to superparasitism. A long-term experiment was conducted to determine the parasitoid densities (0, 2, 4, 6, 8, or 10 per bottle) that most effectively suppress weevils in milled rice during 6 months of storage in 1-1 bottles. To simulate repetitive release of parasitoid, the same number of parasitoids was introduced after each monthly sampling. The number of maize weevils decreased as parasitoid density increased. The best control was obtained with 10 female parasitoids per bottle. At this density, the number of emerged weevil remained stable from the third to the sixth month. Based on the short-term experiment, a parasitoid-host ratio of 1:47 will produce the largest number of parasitoids. Based on the long-term experiment, a parasitoid-host ratio of 1:30 will provide the best control of maize weevils in a monthly release program. The current results indicate that large-scale experiments on biological control of the maize weevil with A. calandrae are now needed.


Xs: 3.7095544 Ys: -0.09668152 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: A longitudinal association between the traditional Japanese diet score and incidence and mortality of breast cancer—an ecological study abstract: The traditional Japanese diet is considered one of the important factors of health and longevity in Japanese people. Breast cancer is the most common cancer among women in the world. However, the association between the traditional Japanese diet and breast cancer is unclear. The purpose of this study was to investigate the longitudinal association between the traditional Japanese diet score (TJDS) with the incidence and mortality of breast cancer in an ecological study.
Food supply and breast cancer incidence and mortality by country were obtained from an international database. TJDS by country was calculated from nine food groups and the total score ranged from −9 to 9, with higher scores indicating greater adherence to a traditional Japanese diet. Longitudinal associations of interaction between TJDS and fiscal year on breast cancer incidence and mortality were investigated in 139 countries with populations of 1 million or greater. The longitudinal analysis was evaluated using four linear mixed-effect models with different adjustment covariables.
Many countries with high scores on TJDS had lower distributions of breast cancer incidence and mortality in 1990–2017. Longitudinal analysis using a linear mixed-effect model controlled for socio-economic and lifestyle covariables showed that the interaction between TJDS and fiscal year was significantly associated with incidence of breast cancer (−0.453 ± 0.138, p < 0.01) and mortality of breast cancer (−0.455 ± 0.135, p < 0.001).
This longitudinal analysis suggested that a traditional Japanese diet has been associated with lower breast cancer incidence and mortality worldwide in recent years.


Xs: 2.791224 Ys: 0.4406308 Publish year: 2013 keyword: thai__longevity_diet source: Thai title: The prevalence of high sodium intake among hypertensive patients at hypertension clinic, Siriraj Hospital abstract: To find the prevalence of excessive salt intake among hypertensive patients in hypertension (HT) clinic at Siriraj Hospital. In addition, to correlate the epidemiologic characteristics of the studied group with high salt diet.
A cross-sectional study was conducted among 320 hypertensive patients in HT clinic at Siriraj Hospital from September 2010 to January 2011. Epidemiologic data, e.g., age, sex, body mass index, duration of treatment, education level, salary, frequency of salty food consumed/week and clinical data, e.g., renal function, (creatinine clearance, CCr) and anti-hypertensive drug(s) received were collected using pre-defined questionnaires. All volunteers were asked to collect 24-hour urine for 2 days to determine average daily amount of urine sodium (UNa). Those 24-hour UNa > or = 100 mmol/ day were considered high salt intake. Correlations of high daily salt intake with all data collected were done.
The prevalence of high salt intake was 73.4%. The mean total daily Na intake was 148 mmol/day i.e. 3.4 g of Na/day When the influence of clinical characteristics on the risks of high salt intake was carried out, there were 2.42, 4.00 and 2.88 fold increases among those who have higher education level, those who have CCr > or = 60 ml/min/1.73 m2, and those who knew that salt could increase blood pressure (BP), respectively. About three-quarters (76.3%) of those patients who knew the effect of salt on BP consumed high salt diet.
The present study revealed that nearly three-quarters of hypertensive patients who attended the HT clinic still consumed high salt diet. Most patients who knew the effect of dietary salt on BP level ignored restriction about salt intake. In addition, those patients with higher education and CCr > or = 60 ml/min/1.73 m2 also consumed high Na diet.


Xs: 3.3203588 Ys: -0.14335023 Publish year: 2022 keyword: thai__longevity_diet source: Thai title: Applying the PDSA cycle to a group activity promoting lifestyle change for the active ageing of older Thai adults – a focused ethnography abstract: Background
The proportion of the older Thai population is increasing rapidly. Lifestyle may impact active ageing in later life. Interventions that empower older Thai adults to initiate and carry out lifestyle changes are needed. This study applied the Plan-Do-Study-Act (PDSA) cycle, a tool for improving lifestyle changes, with the aim of exploring interactions among older Thai adults when participating in group activities.

Method
Focused ethnography was used based on participant observations, field notes and video recordings of 15 older Thai adults aged 62–78 years.

Results
Older Thai adults faced difficulties at the beginning since they were unfamiliar with initiating and carrying out lifestyle changes according to the PDSA concept. This provided a learning opportunity enabling older Thai adults to reach their individual goals of lifestyle change.

Conclusions
The PDSA cycle has the potential to empower older adults in group contexts to promote lifestyle changes related to active ageing.


Xs: 4.894208 Ys: -1.6984985 Publish year: 2015 keyword: thai__longevity_diet source: Thai title: SIRT1 activation ameliorates hyperglycaemia by inducing a torpor-like state in an obese mouse model of type 2 diabetes abstract: Aims/hypothesis:
Nutrient overabundance and diminished physical activity underlie the epidemic of obesity and its consequences of insulin resistance and type 2 diabetes. These same phenomena, obesity and insulin resistance, are also observed in mammals as they ready themselves for the nutrient deprivation of winter, yet their plasma glucose does not rise. Given the role of silent information regulator 2 (Sir2) and its mammalian orthologue, Sirt1, in survival and life extension during energy deprivation, we hypothesised that enhancing its activity may reduce the insensible energy loss engendered by hyperglycaemia and glycosuria.

Methods:
At 8 weeks of age, db/db and db/m mice were randomised to receive the SIRT1 activator SRT3025 milled in chow (3.18 g/kg) or regular chow and followed for a further 12 weeks.

Results:
When compared with vehicle, SIRT1 activation greatly improved glycaemic control, augmented plasma insulin concentrations, increased pancreatic islet beta cell mass and elevated hepatic expression of the beta cell growth factor, betatrophin in db/db mice. Despite the dramatic reduction in hyperglycaemia, db/db mice displayed worsening insulin resistance, diminished physical activity and further weight gain. These findings along with reduced food intake and reduction in body temperature resembled torpor and hibernation. By contrast, SIRT1 activation conferred only minimal changes in non-diabetic db/m mice.

Conclusions/interpretation:
While reducing hyperglycaemia and promoting beta cell expansion, enhancing the activity of SIRT1 facilitates a phenotypic change in a db/db mouse model of diabetes to one that more closely resembles the physiological state of torpor or hibernation.


Xs: 6.528949 Ys: -0.929737 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Efficacy and safety studies on predatory mite, Neoseiulus longispinosus (Evans) against two spotted spider mite, Tetranychus urticae Koch under laboratory and greenhouse conditions abstract: The present study was conducted to determine the effective predator-prey ratio of N. longispinosus at Insectary, Department of Entomology, Tamil Nadu Agricultural University, Coimbatore during the September 2014 to April 2015. The results revealed that Predator-prey ratio 1:10 was quite effective to other predator-prey ratios, where it contributed the mean mite reduction of 97.32 and 55.05 per cent in the laboarortory and greenhouse respectively. Further, the greenhouse study indicated that next to 1:10, predator-prey ratios 1:20 and 1:30 were equally effective in reducing the spider mite population with mean reduction of 46.02 and 39.76 percent respectively. In safety studies, dicofol was found to be highly toxic to adults (LC50 = 0.006 ppm) followed by Fenpyroximate (0.026 ppm), Fenazaquin (0.084 ppm), propargite (0.091ppm). Spiromesifen was found to be moderately toxic (0.524 ppm) whereas, hexythiazox was found to be less toxic with higher LC50 value of 1.641 ppm.


Xs: 4.792484 Ys: 2.4572077 Publish year: 2019 keyword: thai__longevity_diet source: Thai title: Antimetabolic Syndrome Effect of Phytosome Containing the Combined Extracts of Mulberry and Ginger in an Animal Model of Metabolic Syndrome abstract: Due to the antimetabolic syndrome effect of mulberry and ginger together with the advantages of the synergistic effect and phytosome encapsulation technique, we hypothesized that phytosome containing the combined extracts of mulberry and ginger (PMG) should be able to manage MetS. PMG was developed and assessed the phenolic content and biological activities associated with the pathophysiology of MetS. The antimetabolic syndrome effect and the possible underlying mechanisms in the animal model of MetS were also assessed. Male Wistar rats induced MetS by subjecting to a 16-week high-carbohydrate high-fat diet. MetS rats were orally given PMG at doses of 50, 100, and 200 mg/kg for 21 days. They were determined metabolic parameter changes in serum, histomorphology changes of adipose tissue, the inflammatory cytokines such as IL-6 and TNF- α , oxidative stress status, PPAR- γ , and HDAC3 in adipose tissue. Our in vitro data showed that PMG increased phenolic contents and biological activities. PMG significantly improved MetS parameters including body weight gain, lipid profiles, plasma glucose, HOMA-IR, and ACE. In addition, the density and size of adipocyte, adiposity index, and weights of adipose tissues were also improved. Moreover, the decrease in TNF- α and IL-6, oxidative stress status, and HDAC3 expression together with the increase in PPAR- γ expression in adipose tissue was also observed. These data suggest that PMG exhibit antimetabolic syndrome and the possible underlying mechanism may be associated partly with the modulation effect on HDAC3, PPAR- γ , and adipose tissue. In addition, PMG also improves oxidative stress and inflammation in MetS. Therefore, PMG can be served as the potential supplement to manage MetS. However, a clinical trial study is essential to confirm this health benefit.


Xs: 4.3083415 Ys: 4.6571045 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: Effect of fiber source diet supplement on growth performance, carcass quality, oxidative stress and intestinal morphology in Thai native chicken (Pradu Hang dum) abstract: Dietary fiber was used for reduce feed cost in local animal production. However, other advantages effects were interesting to study. Therefore, the objective of this research was to investigated effect of fiber source diet on performance, carcass quality, oxidative stress and intestinal morphology in Thai native chicken. A total of 300 one-day-old (mixed sex) crossbred native chicks (Pradu Hang dum) were randomly assigned to 5 treatments in completely randomized design (CRD). Each treatment had 10 replicates with the crossbred native chickens 6 bird/replicates (1 to 12 weeks of age) were given different levels of banana stem and Napier grass. Treatment diets received as follows a basal diet; 100%, no supplement or control group (CON), basal diet; 95%, 90% supplemented with the banana stem at 50 g/kg, 100 g/kg (BS 5%, BS 10%) of diet, respectively, and basal diet; 95%, 90% supplemented with the Napier grass at 50 g/kg, 100 g/kg (NG 5%, NG 10%) of diet, respectively. The results of the study showed that the use of fiber source: banana stem at 50 g/kg and Napier grass 100 g/kg of the diet improved growth performance. The result showed benefits to increase body weight, improve feed conversion ratio (FCR) and feed cost per gain (FCG), improve to gut health by increase villus height (VH), Villus width (VW) in duodenal and jejunal small intestine morphology, reduced malondialdehyde (MDA) levels in serum (p < 0.001). In addition, significantly higher thigh meat percentage (p < 0.05) without effecting visceral weight and overall carcass percentage.


Xs: 6.3486104 Ys: -1.0297499 Publish year: 2024 keyword: thai__longevity_diet source: Thai title: Life-history traits of Aedes aegypti (Linnaeus) distributed across a latitudinal range of 23 °N-6 °S abstract: The growth and associated traits of Aedes aegypti (L.) mosquitoes may adapt and evolve in response to the costs associated with body size in relation to latitudinal variation. We analyzed the life-history traits and energy reserves of field-collected mosquitoes from Taiwan, Thailand, and Indonesia along a latitudinal range spanning from 23°N to 6°S. A U-shaped relationship between body size and latitude was observed. Our study demonstrated the role of latitudinal temperature variations in determining the body size patterns of Ae. aegypti. Notably, the body size of the northern populations (from Taiwan) was significantly larger than those of the tropical populations from Thailand and Indonesia. Models have demonstrated that regional precipitation levels may contribute to body trait variations in certain high-latitude populations in Thailand. However, Indonesian populations have high development rates and large body sizes, indicating the involvement of other physiological traits in determining mosquito body size. The reproductive output of the adult females in this study was positively correlated with body size, but our measure of longevity did not covary significantly with the body size. By contrast, the reproductive output of mosquito-tested populations was in inverse proportion to longevity. Additionally, the mean teneral glycogen levels in the Indonesian and Thai populations were 2.5 times higher than those in the Taiwanese populations. The Indonesian and Thai populations had low mean generation and doubling times, resulting in a high intrinsic rate of increase compared with that of the Taiwanese populations, despite the Taiwanese populations having the highest net reproduction rate.


Xs: 2.852146 Ys: 0.080608904 Publish year: 2016 keyword: thai__longevity_diet source: Thai title: Clinical characteristics and outcomes of the oldest old people with type 2 diabetes – perspective from a tertiary diabetes center in Thailand abstract: Background: Advance in medicine has led to an increase in life expectancy of elderly diabetic patients especially on the growing population called the “oldest old”, those in their mid-80s upwards. The aim of this study is to describe clinical characteristics and outcomes of “oldest old” patients in a specialized diabetes center.

Methods: A retrospective review was conducted on medical records of type 2 diabetes who were older than 85 years at Theptarin hospital from September 2014 to August 2015.

Results: During the study period, there were 143 oldest old diabetic patients who visited our hospital regularly. Of the 133 active follow-up patients (median time of follow-up 15 years, range 1-30 years), 70.7 % was female, the mean age of onset was 68.3±11.5 years and duration of diabetes was 20.1±11.1 years. According to the Charlson co-morbidity index (CCI), 35.3% of patients were classified as having severe co-morbidities. The mean A1C, blood pressure, LDL were 6.7±1.1%, 132/65 mmHg and 80±29 mg/dl respectively. 66.9% of patients had tight glycemic control (A1C <7%) while 12.0% had poor control (A1C >8%). Oral hypoglycemic agent (OHA) dual therapy was the most common treatment (26.3%) followed by OHA monotherapy (22.6%), insulin alone (19.5%), diet therapy alone (12.7%), and insulin plus OHA (8.3%). Hypoglycemia was found in 10.5% of patients in previous 12 months. Diabetic retinopathy, chronic kidney disease, cardiovascular disease, and stroke were presented in 23.4%, 54.9%, 15.8%, 18.0% of patients, respectively. Among patients whose received diabetic medications and resulted in very low level of A1C (A1C less than 6.0%), only 20.0% underwent deintensification.

Conclusions: Our results revealed that real-world clinical outcomes of extreme elderly diabetic patients were diverse and being too "aggressive" diabetes treatment with older patients did occur frequently. Decision making in older people with diabetes is complex as chronic co-morbidities are very common.


Xs: 4.08248 Ys: 1.1483839 Publish year: 2013 keyword: thai__longevity_diet source: Thai title: Effects of mindfulness meditation on serum cortisol of medical students abstract: Mindfulness meditation is a method to relax the mind that decreases stress, which otherwise would increase serum cortisol. So, mindfulness meditation should decrease serum cortisol.
To study the effect of mindfulness meditation on mental health by using Thai GHQ28 questionaire and study the effect of mindfulness meditation on stress by using serum cortisol.
Volunteer subjects were 30 second year medical students, aged 19.1 +/- 0.55 year olds (range 18-20) from Srinakharinwirot University. They were screened by Thai GHQ28 and blood was drawn to measure cortisol at 8:00 am before and after a four-day mindfulness meditation programme. The comparison of Thai GHQ28 scores and serum cortisol levels before and after meditation were analysed by paired t-test.
The subjects were 66.77% female and 33.33% male. The average score of Thai GHQ28 before and after the mindfulness meditation was 1.50 (SD 2.53) and 0.77 (SD 2.08) respectively. The average serum cortisol levels before mindfulness meditation was 381.93 nmol/L (SD 97.74) becoming significantly lower after mindfulness meditation 306.38 nmol/L (SD 90.95). The difference was statistically significant in cortisol level, but not statistically significant in Thai GHQ28.
Mindfulness meditation lowers the cortisol levels in the blood suggesting that it can lower stress and may decrease the risk of diseases that arise from stress such as psychiatric disorder, peptic ulcer and migraine. Then, mindfulness meditation should be used in combination with standard treatment.


Xs: 5.944128 Ys: 1.0286995 Publish year: 2024 keyword: thai__longevity_diet source: Thai title: Diverse effects of a Cyperus rotundus extract on glucose uptake in myotubes and adipocytes and its suppression on adipocyte maturation abstract: Cyperus rotundus rhizomes have been used in longevity remedies in Thailand for nourishing good health, which led us to investigate the effect on energy homeostasis, especially glucose utilization in myotubes and adipocytes, and on inhibition of lipogenesis in adipocytes. The results showed that an ethyl acetate extract of C. rotundus rhizomes (ECR) containing 1.61%w/w piceatannol, with a half-maximal concentration of 17.76 ± 0.03 μg/mL in 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay, caused upregulation and cell-membrane translocation of glucose transporters GLUT4 and 1 in L6 myotubes but downregulation and cytoplasmic localization of GLUT4 expression in 3T3-L1 adipocytes and was related to the p-Akt/Akt ratio in both cells, especially at 100 μg/mL. Moreover, ECR (25–100 μg/mL) significantly inhibited lipid accumulation via Adenosine Monophosphate-Activated Protein Kinase (AMPK), Acetyl CoA Carboxylase (ACC), and Glycogen Synthase Kinase (GSK) pathways. Its immunoblot showed increased expression of p-AMPKα/AMPKα and p-ACC/ACC but decreased expression of p-Akt/Akt and p-GSK3β/GSK3β in 3T3-L1 adipocytes. Moreover, the decreased expression of the adipogenic effectors, perilipin1 and lipoprotein lipase, in ECR-incubated adipocytes (50 and 100 μg/mL) indicated reduced de novo lipogenesis. Our study elucidated mechanisms of C. rotundus that help attenuate glucose tolerance in skeletal muscle and inhibit lipid droplet accumulation in adipose tissue.


Xs: 4.418616 Ys: -0.9512894 Publish year: 2010 keyword: thai__longevity_diet source: Thai title: Relationship between food polyamines and gross domestic product in association with longevity in Asian countries abstract: The relationship between gross domestic pro- duct (GDP) and dietary profile, with a focus on polyamine intake, was investigated in 35 Asian countries. Data on food supply, GDP, and health condition were collected from databases of the United Nations, the International Monetary Fund, and the World Health Organization, respectively. The amount of polyamine intake from food was estimated using polyamine concentrations listed in published sources. The amounts of putrescine, spermidine, spermine, and total polyamines in 1000 kcal of food in Asian countries were 39.07 ± 17.98, 33.74 ± 14.35, 14.05 ± 6.60 and 86.85 ± 33.96 μmol/1000 kcal, respectively. Putrescine, spermidine, and spermine constituted 44, 39, and 17% of total polyamine, respectively. Vegetables contributed the largest amount of both putrescine and spermidine and the second largest amount of spermine (45.5%, 62.2% and 27.2% of total putrescine, spermidine, and spermine, respectively). Meat was the richest source of spermine and contributed the greatest amount (50%) of this polyamine. We showed a significant positive association between GDP and the amount of polyamine per 1000 kcal of food. Lifespan was associated with both GDP and the amount of polyamine per energy quotient of food. As several basic research studies have shown that polyamines help prolong longevity, it follows that polyamines may have a role in determining the lifespan of humans.


Xs: 3.6304834 Ys: 0.6113387 Publish year: 2015 keyword: thai__longevity_diet source: Thai title: A perspective on vegetarian dietary patterns and risk of metabolic syndrome abstract: The vegetarian dietary pattern is traditionally a plant-based diet that includes fruits, vegetables, cereals, legumes, nuts, vegetable oils, soya, and possibly dairy products and/or eggs. Vegetarians and other populations who follow a plant-based dietary pattern enjoy longevity. Specifically, vegetarian dietary patterns have been associated with a lower risk for developing IHD, type 2 diabetes, hypertension, specific cancers, lower all-cause mortality and reduction in cause-specific mortality. The prevalence of the metabolic syndrome (MetS) in the USA is approximately 20 % and is currently increasing in developing countries in line with the obesity epidemic. The health care costs associated with the MetS are on a magnitude of 1·6 overall compared with healthy individuals, which makes it an important public health problem. Current evidence from several cross-sectional and case-control studies shows an association between consumption of a vegetarian dietary pattern and a reduced prevalence or risk of developing the MetS. There is a need for further research to be conducted, particularly prospective cohort studies to evaluate the effect of vegetarian dietary patterns on reducing the incidence of the MetS and, clinical trials should be designed to explore vegetarian dietary patterns for the reversal of the MetS in high-risk populations. This research could contribute to reduce the societal and economic burdens associated with the disorder.


Xs: 8.17442 Ys: 3.8590395 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Inhibition of Oxidative Stress through the Induction of Antioxidant Enzymes of Pigmented Rice Bran in HEK-293 Cells abstract: The cellular antioxidant enzymes play an essential role on the protection of oxidative stress. Pigmented rice bran is the major sources of phytochemicals and elicits antioxidant property. However, the effects of pigmented rice bran on the upregulation of cellular antioxidant enzymes are incompletely understood. In this study, we demonstrated that treatment of HEK-293 cells with pigmented rice bran extracts (200 ìg/mL) from Red Hawm, Red Rose, Black Sukhothai-II, and Kum Doisaket strains significantly inhibited H2O2-induced intracellular ROS production. These pigmented rice bran extracts induced mRNA expression of glutathione peroxidase-1 (GPx-1), glutathione reductase and catalase. Additionally, treatment with these rice bran extract also increased protein expression of GPx-1 and catalase. Thus, these pigmented rice bran extracts exert the cellular antioxidant effects by decreasing ROS generation as well as increasing the production of antioxidant enzymes.


Xs: 5.1622624 Ys: -1.1654532 Publish year: 2014 keyword: thai__longevity_diet source: Thai title: Vertebral Bomb Radiocarbon Suggests Extreme Longevity in White Sharks abstract: Conservation and management efforts for white sharks (Carcharodon carcharias) remain hampered by a lack of basic demographic information including age and growth rates. Sharks are typically aged by counting growth bands sequentially deposited in their vertebrae, but the assumption of annual deposition of these band pairs requires testing. We compared radiocarbon (Δ(14)C) values in vertebrae from four female and four male white sharks from the northwestern Atlantic Ocean (NWA) with reference chronologies documenting the marine uptake of (14)C produced by atmospheric testing of thermonuclear devices to generate the first radiocarbon age estimates for adult white sharks. Age estimates were up to 40 years old for the largest female (fork length [FL]: 526 cm) and 73 years old for the largest male (FL: 493 cm). Our results dramatically extend the maximum age and longevity of white sharks compared to earlier studies, hint at possible sexual dimorphism in growth rates, and raise concerns that white shark populations are considerably more sensitive to human-induced mortality than previously thought.


Xs: 4.4146175 Ys: 2.8294265 Publish year: 2022 keyword: thai__longevity_diet source: Thai title: Antidyslipidemic, Antioxidant, and Anti-inflammatory Effects of Jelly Drink Containing Polyphenol-Rich Roselle Calyces Extract and Passion Fruit Juice with Pulp in Adults with Dyslipidemia: A Randomized, Double-Blind, Placebo-Controlled Trial abstract: Oxidative stress and inflammation play key roles in the pathophysiology in the pathophysiology of dyslipidemia, which are positive risks that increase atherosclerosis leading to important healthcare problems. Therefore, we aimed to study the antioxidant, anti-inflammatory, and lipid-lowering effects of jelly drink containing polyphenol-rich roselle calyces extract and passion fruit juice with pulp concentrate (RP jelly drink) in comparison to a placebo jelly drink for 8 weeks. Forty-three adults with dyslipidemia were randomly assigned into two groups: the RP jelly drink group and the placebo group. Glucose, total cholesterol (TC) triglyceride (TG), low-density lipoprotein-cholesterol (LDL-C), high-density lipoprotein-cholesterol (HDL-C), oxidative stress biomarkers, inflammatory parameters, and monocyte chemotactic protein-1 (MCP-1) were measured with fasting blood samples at baseline, 4 weeks and 8 weeks of intervention. Results showed a significant decrease in LDL-C and TG, respectively, after 8 weeks of RP jelly drink consumption (LDL-C: 107.63 ± 22.98 m g / d L ; TG: 109.79 ± 38.83 m g / d L ) compared to baseline measurements (LDL-C: 128.43 ± 32.74 m g / d L ; TG: 132.33 ± 75.11 m g / d L ). These may be possible due to reduced inflammation and improvements in oxidative stress, as demonstrated by the reduction of tumor necrosis factor- (TNF-) α and malondialdehyde (MDA), and the enhancement of glutathione (GSH) after consuming the RP jelly drink for 8 weeks. However, no significant differences of treatment on glucose, total cholesterol, MCP-1, interleukin-6, and interleukin-10 were observed. In conclusion, daily consumption of RP jelly drink for 8 weeks resulted in significant improvement in lipid profiles in subjects with dyslipidemia. However, more research is needed to assess its nutritional and functional potential.


Xs: 5.82867 Ys: -0.3933802 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: In Vitro and In Vivo Evaluation for Antioxidant and Anti-Diabetic Properties of Cyperus rotundus L. Kombucha abstract: Cyperus rotundus L. exhibits promising potential for the development of functional foods due to its documented pharmacological and biological activities. This study investigated the antioxidant and anti-diabetic properties of C. rotundus kombucha. The results demonstrated potent antioxidant activity with an IC50 value of 76.7 ± 9.6 µL/mL for the DPPH assay and 314.2 ± 16.9 µL/mL for the ABTS assay. Additionally, the kombucha demonstrated alpha-glucosidase inhibitory with an IC50 value of 142.7 ± 5.2 µL/mL. This in vitro antioxidant potential was further validated in vivo using Drosophila. Drosophila fed a high-sugar diet and supplemented with pure kombucha revealed significant increases in DPPH and ABTS free radical scavenging activity. Drosophila on a high-sugar diet supplemented with varying kombucha concentrations manifested enhanced resistance to oxidative stresses induced by H2O2 and paraquat. Concurrently, there was a notable decline in lipid peroxidation levels. Additionally, significant upregulations in CAT, SOD1, and SOD2 activities were observed when the high-sugar diet was supplemented with kombucha. Furthermore, in vivo assessments using Drosophila demonstrated significant reductions in alpha-glucosidase activity when fed with kombucha (reduced by 34.04%, 13.79%, and 11.60% when treated with 100%, 40%, and 10% kombucha, respectively). A comprehensive GC-MS and HPLC analysis of C. rotundus kombucha detected the presence of antioxidative and anti-glucosidase compounds. In conclusion, C. rotundus kombucha exhibits considerable antioxidant and anti-diabetic properties, demonstrating its potential as a beneficial beverage for health promotion.


Xs: 3.9294214 Ys: 4.387781 Publish year: 2020 keyword: thai__longevity_diet source: Thai title: The International Conference on Food and Applied Bioscience 2020: Insights for Research and Industry 4.0 Bioethanol Production Using Cellulose-Rich Corncob Residue by Thermotolerant Yeasts abstract: Thermotolerant yeasts are usually employed for bioethanol production from lignocellulosic biomass via the separate hydrolysis and fermentation (SHF) and simultaneous saccharification and fermentation (SSF) process. However, SSF process shows good advantages such as reducing the risk of contamination, cooling cost, and overall process time. In addition, thermotolerant yeasts can produce bioethanol and grow well at the elevated temperature which is suitable for the enzymatic hydrolysis of lignocellulosic biomass. In this study, four isolates of thermotolerant yeasts were screened and selected as a platform for secondary bioethanol production from cellulose-rich corncob (CRC) residue, a waste from corncob-xylooligosaccharides production, via SHF process at 42°C. Among those isolates, TC-5 and G3 were the promising thermotolerant strains for bioethanol production from CRC hydrolysate with ethanol concentration of 18.38±0.32 and 19.05±0.41 g/L, respectively. Moreover, both strains were identified based on nucleotide sequence of 26S rDNA as Saccharomyces cerevisiae TC-5 and Candida glabrata G3, respectively. The effect of temperature on bioethanol production via SHF and SSF processes by both strains was also investigated at 35-42°C. The result from SHF process showed that strain TC-5 and G3 exhibited the maximum bioethanol production with the ethanol concentration of 18.39±0.35 and 19.48±0.44 g/L, with theoretical ethanol yield of 66.65±1.25 and 70.60±3.69%, and ethanol productivity of 0.256±0.005 and 0.271±0.014 g/L/h, respectively. While, bioethanol production via SSF process demonstrated that strain TC-5 showed the maximum bioethanol production with ethanol concentration, and theoretical ethanol yield of 21.82±1.78 g/L, and 79.78±6.45%, respectively. In addition, strain G3 was also showed the high bioethanol production with ethanol concentration, and theoretical ethanol yield of 21.56±1.98 g/L, and 78.13±7.18%, respectively. However, C. glabrata is one of opportunistic human pathogenic yeast. Therefore, thermotolerant S. cerevisiae TC-5 is selected as one of the promising yeast strain for bioethanol from CRC residue via SSF process dues to its biosafety and high ethanol production efficacy.


Xs: 4.641501 Ys: -1.0071255 Publish year: 2018 keyword: thai__longevity_diet source: Thai title: A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses abstract: To what extent immune responses against the gut flora are compartmentalized within mucosal tissues in homeostatic conditions remains a much-debated issue. We describe here, based on an inducible AID fate-mapping mouse model, that systemic memory B cell subsets, including mainly IgM + B cells in spleen, together with IgA + plasma cells in spleen and bone marrow, are generated in mice in the absence of deliberate immunization. While the IgA component appears dependent on the gut flora, IgM memory B cells are still generated in germ-free mice, albeit to a reduced extent. Clonal relationships and renewal kinetics after anti-CD20 treatment reveal that this long-lasting splenic population is mainly sustained by output of B cell clones persisting in mucosal germinal centers. IgM-secreting hybridomas established from splenic IgM memory B cells showed reactivity against various bacterial isolates and endogenous retroviruses. Ongoing activation of B cells in gut-associated lymphoid tissues thus generates a diversified systemic compartment showing long-lasting clonal persistence and protective capacity against systemic bacterial infections.


Xs: 5.5719423 Ys: -0.139029 Publish year: 2017 keyword: thai__longevity_diet source: Thai title: Feeding Asian pangolins: An assessment of current diets fed in institutions worldwide abstract: Pangolins are ant specialists which are under intense threat from the illegal wildlife trade. Nutrition has notoriously been their downfall in captivity and is still an issue in regards to rescue and rehabilitation. We analyzed the nutrient content of diets used by institutions that are successfully keeping Asian pangolins and to assess the variety of the ingredients and nutrients, compared these with the nutritional requirements of potential nutritional model species. We performed intake studies at five institutions and also had data from three other institutions. We also analyzed five different wild food items to use as a proxy of wild diet. We observed two categories of captive diets: those mostly or completely composed of insects and those high in commercial feeds or animal meat. Nutrient values were broad and there was no clear rule. The non-protein energy to protein energy ratio of the diets were much higher than the wild food items, more so for those which receive less insects. The average contribution of carbohydrate, fat, and protein energy were also further away from the wild samples the less insects they contained. The previously suggested nutritional model for pangolins is the domestic dog which is supported by our relatively large nutrient ranges of apparently successful diets, however, due to their highly carnivorous nature; the upper most nutrient intake data are not consistent with this and favor the feline nutrient recommendations. We are unable to render a conclusion of what model is more appropriate based on our data collected.


Xs: 3.2555645 Ys: 0.4877303 Publish year: 2014 keyword: thai__longevity_diet source: Thai title: Computer Game Use and Television Viewing Increased Risk for Overweight among Low Activity Girls: Fourth Thai National Health Examination Survey 2008-2009 abstract: Studies of the relationship between sedentary behaviors and overweight among children and adolescents show mixed results. The fourth Thai National Health Examination Survey data collected between 2008 and 2009 were used to explore this association in 5,999 children aged 6 to 14 years. The prevalence of overweight defined by the age-and gender-specific body mass index cut-points of the International Obesity Task Force was 16%. Using multiple logistic regression, computer game use for more than 1 hour a day was found to be associated with an increased risk of overweight (adjusted odds ratio (AOR) = 1.4; 95% confidence interval: 1.02–1.93). The effect of computer game use and TV viewing on the risk for overweight was significantly pronounced among girls who spent ≤3 days/week in 60 minutes of moderate-intensity physical activity (AOR = 1.99 and 1.72, resp.). On the contrary, these sedentary behaviors did not exert significant risk for overweight among boys. The moderating effect on risk of overweight by physical inactivity and media use should be taken into consideration in designing the interventions for overweight control in children and adolescents. Tracking societal changes is essential for identification of potential areas for targeted interventions.


Xs: 5.1222115 Ys: 2.7026668 Publish year: 2022 keyword: thai__longevity_diet source: Thai title: Dietary Vitamin A Intake and Circulating Vitamin A Concentrations and the Risk of Three Common Cancers in Women: A Meta-Analysis abstract: Background:
According to relevant clinical research, dietary and circulating antioxidants vitamin A are connected with the risk of breast, cervical, and ovarian cancer in women. However, there was inconsistency between the findings. We completed this meta-analysis at the right moment to address this contradiction of the problem.

Methods:
Web of Science, Embase, and PubMed databases were searched using the proposed search strategy and filtered using the inclusion and exclusion criteria as well as the NOS quality score. As of May 2022, low intake or low concentration was used as a control, and odds ratio (OR) or relative risk (RR) and ninety-five percent confidence intervals (95% CI) were extracted for high intake. Stata 12.0 was used to process the data.

Results:
Our meta-analysis included a total of 49 studies, 29 on breast cancer, 10 on ovarian cancer, and 10 on cervical cancer. There were 38 case-control studies included, with 25,363 cases and 42,281 controls; there were 11 cohort studies included, 1,334,176 individuals were followed up, and finally 9496 obtained cancer. The pooled OR value results were as follows: diet or supplements (OR = 0.83, 95% CI 0.76-0.90, I 2 = 56.1%) and serum or plasma (OR = 0.96, 95% CI 0.86-1.09, I 2 = 29.5%). Subgroup analyses were performed according to cancer type, diet or supplements, serum or plasma, study type, and geographic regions.

Conclusions:
In North American and Asian populations, high dietary consumption of vitamin A or supplements decreases the incidence of three cancers in women, with breast and ovarian cancers being more significant. However, high circulating vitamin A concentrations were not significantly connected with the risk of the three malignancies.


Xs: 6.387853 Ys: -0.9821055 Publish year: 2016 keyword: thai__longevity_diet source: Thai title: Redescription of immature stages of the soybean looper (Lepidoptera: Noctuidae: Plusiinae) abstract: Chrysodeixis includens
(Walker) is a characteristic Plusiinae (Lepidoptera: Noctuidae) species from the Western Hemisphere. The larva have already been found feeding on several different plant families, including economic value crops such as soybeans. This species coexists and can be confused with
Rachiplusia nu
(Guenée) (Lepidoptera: Noctuidae) in soybean crops. Furthermore, some studies indicate that
C
.
includens
shows tolerance to various insecticides, leading to differentiation among these two species to be most important in relation to control procedures to be undertaken. To contribute to the correct identification of
C
.
includens
we made detailed redescriptions of all preimaginal stages (egg, larva, and pupa). Immature stages of
C
.
includens
were reared in laboratory under controlled conditions of 27±2 °C, 70–75% relative humidity, and 14:10 (light/dark) photoperiod. We consider opportune detection of preimaginal stages of
Chrysodeixis includens
will help to control this pest species, especially at admissible economical levels.


Xs: 7.8704367 Ys: 2.5692623 Publish year: 2024 keyword: thai__longevity_diet source: Thai title: Antibacterial activity of Dioscorea bulbifera Linn. extract and its active component flavanthrinin against skin-associated bacteria abstract: Background
Dioscorea bulbifera Linn. has been used for wound care in Thailand. However, a comprehensive evaluation of its antibacterial activity is required. This study aimed to investigate the antibacterial efficacy of D. bulbifera extract against skin-associated bacteria and isolate and characterize its active antibacterial agent, flavanthrinin.

Methods
Air-dried bulbils of D. bulbifera were pulverised and extracted with hexane, dichloromethane, ethyl acetate, methanol, ethanol, and distilled water; vacuum filtered; concentrated; freeze-dried; and stored at -20 ºC. Antibacterial activity of the extracts was assessed using microdilution techniques against several skin-associated bacteria. Thin-layer chromatography (TLC) bioautography was used to identify the active compounds in the extract, which were fractionated by column chromatography and purified by preparative TLC. The chemical structures of the purified compounds were analysed using nuclear magnetic resonance (NMR). The cytotoxicity of the extract and its active compounds was evaluated in Vero cells.

Results
The ethyl acetate extract exhibited distinct inhibition zones against bacteria compared to other extracts. Therefore, the ethyl acetate extract of D. bulbifera in the ethyl acetate layer was used for subsequent analyses. D. bulbifera extract exhibited antibacterial activity, with minimum inhibitory concentrations (MICs) of 0.78–1.56 mg/mL. An active compound, identified through TLC-bioautography, demonstrated enhanced antibacterial activity, with MICs of 0.02–0.78 mg/mL. NMR analysis identified this bioactive compound as flavanthrinin. Both D. bulbifera extract and flavanthrinin-containing fraction demonstrated potent antibacterial activity against Staphylococcus aureus, methicillin-resistant S. aureus (MRSA), and S. epidermidis. The flavanthrinin containing fraction demonstrated low cytotoxicity against Vero cells, showing CC50 values of 0.41 ± 0.03 mg/mL. These values are lower than the MIC value, indicating that this fraction is safer than the initial ethyl acetate extract.

Conclusions
Dioscorea bulbifera extract and its bioactive component flavanthrinin demonstrated significant antibacterial activity against the skin-associated bacteria Staphylococci, including MRSA. Flavanthrinin has potential as a complementary therapeutic agent for managing skin infections owing to its potent antibacterial effects and low cytotoxicity.


Xs: 4.0866027 Ys: 1.6128691 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Association of Oxidative Balance Score with the Metabolic Syndrome in a Sample of Iranian Adults abstract: Objective:
We aimed to assess the association of the oxidative balance score (OBS) with metabolic syndrome (MetS) in adults.

Design:
A population-based cross-sectional study Setting. Health centers from five districts in Tehran, Iran.

Methods:
We recruited 847 participants with an age range of 18-65 years. Dietary intake was assessed by a semiquantitative food frequency questionnaire with 168 items. The OBS was calculated by using the following 13 dietary and nondietary anti- and prooxidant components: dietary antioxidants (selenium, fiber, β-carotene, vitamin D, vitamin C, vitamin E, and folate), dietary prooxidants (iron and saturated and polyunsaturated fatty acids), and nondietary anti- (physical activity) and prooxidants (smoking and obesity). The odds ratio (OR) and 95% confidence interval (CI) of the MetS and its components across tertiles of the OBS were calculated by logistic regression analysis, controlling for age, sex, energy intake, occupation, and educational level.

Results:
The range of OBS was between 16 and 39. Being in the top versus the bottom tertile of the OBS was not associated with the MetS (OR = 0.71, 95% CI 0.48-1.03; P = 0.07), after controlling for potential confounders. Higher OBS score was associated with a lower likelihood of abdominal obesity (OR: 0.55, 95% CI: 0.38-0.81; P = 0.003) and increased diastolic blood pressure (OR: 0.64, 95% CI: 0.41-0.99; P = 0.04). Higher OBS was not associated with other components of the MetS.

Conclusion:
Overall, the present study showed that there was no significant relationship between OBS and MetS in Tehranian adults.


Xs: 5.599583 Ys: -1.2558618 Publish year: 2020 keyword: thai__longevity_diet source: Thai title: Effects of dietary restriction on lifespan, growth, and reproduction of the clam shrimp Eulimnadia texana abstract: Diet has been linked to lifespan in a broad range of animals. In particular, pronounced caloric restriction has been associated with increased longevity. Herein, the relationship of feeding environment and longevity is examined experimentally using Spinicaudatan crustaceans (“clam shrimp”) from the geographically widespread genus Eulimnadia. Two projects examine the effects of food differences on longevity, one comparing food environment early vs later in life and one comparing the effects of dietary restriction on longevity, growth, and reproduction. In the former, dietary restriction increased longevity, but only when diets were reduced later in life. A closer examination of the effects of dietary restriction in the second experiment did not find the expected trade-off of increased longevity and reduced reproductive output in the lowest-food treatment, but instead found an overall increase in both longevity and egg production on the low compared to the high food diet. Finally, a detailed analysis of the relationship of size (carapace length) with egg production was presented. This relationship could serve to obtain a rough estimate of reproductive output potential of fossil clam shrimps, of which typically only the carapace size can be assessed.


Xs: 3.1274216 Ys: -0.043960053 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Health-promoting behaviors among urban and rural older Thai adults with hypertension: A cross-sectional study abstract: Health-promoting behaviors are beneficial for enhancing the older adults’ health, and several factors such as individual, culture, and social factors influence them. Previous studies have shown that their place of residence is associated with healthy lifestyles of older adults; however, the results are inconsistent. This study aimed to 1) compare health-promoting behaviors among urban and rural older Thai adults with hypertension, and 2) determine the predictability of individual characteristics (age, income, perceived health status), and perceived self-efficacy on their health-promoting behaviors. A cross-sectional survey was conducted among 420 older adults using a demographic questionnaire, the Self-Rated Abilities Scale for Health Practice, and the Health Promoting Lifestyle Profile II. Data analysis used descriptive statistics, Pearson’s correlation, and hierarchical regression analysis.

Results indicated that older adults in urban districts had higher perceived self-efficacy and health-promoting behaviors than those in rural locations. Perceived self-efficacy and income were predictors of health-promoting behaviors, accounting for 45.4% of the variance. Nurses can use these findings to develop health interventions aimed at increasing perceived self-efficacy through nursing support. Providing health education to improve older adults’ self-confidence, reduce anxiety and distress may enhance their healthy lifestyle behaviors, particularly those with low income in rural areas who may require more support.


Xs: 3.586032 Ys: -0.3709598 Publish year: 2018 keyword: thai__longevity_diet source: Thai title: Longevity and elderly care: lessons from Japan abstract: Japanese life expectancy is among the highest in the world and it keeps on increasing. Along with the extension of life span, healthy life expectancy is also increasing. Building geriatric hospitals and nursing homes could not cover the necessity. At present, the majority of people want to receive medical care at home. Health promotion and disease prevention at preclinical stage of elderly by diets and physical activity is the only effective resolution.


Xs: 2.5942953 Ys: 0.6262702 Publish year: 2012 keyword: thai__longevity_diet source: Thai title: The Usefulness of Homeostatic Measurement Assessment-Insulin Resistance (HOMA-IR) for Detection of Glucose Intolerance in Thai Women of Reproductive Age with Polycystic Ovary Syndrome abstract: Objectives. To study the cut-off point of Homeostatic Measurement Assessment-Insulin Resistance (HOMA-IR) as a screening test for detection of glucose intolerance in Thai women with polycystic ovary syndrome (PCOS). Study Design. Cross-sectional study. Setting. Department of Obstetrics and Gynecology, Faculty of Medicine Siriraj Hospital. Subject. Two hundred and fifty Thai PCOS women who attended the Gynecologic Endocrinology Unit, during May 2007 to January 2009. Materials and Methods. The paitents were interviewed and examined for weight, height, waist circumference, and blood pressure. Venous blood samples were drawn twice, one at 12-hour fasting and the other at 2 hours after glucose loading. Results. The prevalence of glucose intolerance in Thai PCOS women was 20.0%. The mean of HOMA-IR was 3.53  ±  7.7. Area under an ROC curve for HOMA-IR for detecting glucose intolerance was 0.82. Using the cut-off value of HOMA-IR >2.0, there was sensitivity at 84.0%, specificity at 61.0%, positive predictive value at 35.0%, negative predictive value at 93.8%, and accuracy at 65.6%. Conclusion. HOMA-IR >2.0 was used for screening test for glucose intolerance in Thai PCOS women. If the result was positive, a specific test should be done to prove the diagnosis.


Xs: 3.4421985 Ys: 0.023474231 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Differences of body composition and physical strength among Japanese and Thai older adults living in Chiang Mai, Thailand: an inter-ethnic cross-sectional study abstract: Background
The number of adults aged over 65 years is rapidly increasing in several Southeast Asian countries. Muscle mass decreases with age, leading to sarcopenia. The primary objective of this study was to determine whether differences exist in the body composition and physical strength, according to ethnicity, among community-dwelling Japanese and Thai older adults living in Chiang Mai Province, Thailand.

Methods
A survey was conducted in February and March 2019. Japanese and Thai adults aged ≥ 60 years living in Chiang Mai Province were recruited through community clubs. Participants completed a self-administered questionnaire that enabled collection of data on age, sex, educational background, marital status, annual income, current medical conditions, smoking and alcohol consumption, and exercise habits. Measurements were collected on height, weight, body composition, blood pressure, hand grip, and walking speed for 6 m. Body composition was measured using a standing-posture 8-electrode multifrequency bioimpedance analysis analyzer. Hand grip of each hand was measured with the patient in the standing position using a digital grip dynamometer. Multivariable logistic regression was used to determine factors associated with skeletal muscle mass index (SMI).

Results
Of the total 119 participants, 47 were Japanese (26 men, 21 women) and 72 were Thai (16 men, 56 women). The prevalence of a low SMI was 3/26 (12%), 1/21 (5%), 6/16 (38%), and 5/56 (9%) among Japanese men, Japanese women, Thai men, and Thai women, respectively. The prevalence of low muscle strength was 2/26 (8%), 2/21 (10%), 3/16 (19%), and 13/56 (23%) among Japanese men, Japanese women, Thai men, and Thai women, respectively. There were significant differences between ethnic groups in body mass index for both sexes, percentage body fat in women, SMI in men, and average grip strength in men. Ethnic group, sex, age, and body mass index were independent predictors of SMI.

Conclusions
Ethnicity had a clinically important effect on body composition and physical strength among older Japanese and Thai adults living in a similar environment.


Xs: 6.0835457 Ys: 1.9672073 Publish year: 2022 keyword: thai__longevity_diet source: Thai title: Niger improvement and production in Ethiopia: progress and major challenges abstract: Niger crop is one of the under-utilized oil crops, but very crucial in Ethiopian diets and export system. Despite its importance, many problems have to be addressed through research. Starting from the beginning when a multidisciplinary approach of niger breeding started during the late 1960s century, some efforts have been made to overcome the major limitations of niger production and productivity in Ethiopia. However, there is a minimum application of modern breeding, and many challenges persist. The major challenges that face the niger breeding and production in Ethiopia are the nature of the crop (self-incompatibility), lodging and shattering, low yielding potential, susceptibility to pests, poor agronomic practices, less attention, and low inputs and modern farm technology. These challenges are retarding the breeding and also the production system of the niger. To make niger research more impactful on these challenges, exploiting and the use of novel research techniques which may include gene identification and transformation are very important. Moreover, genomic assisted breeding holds tremendous potential for improving productivity and provides better information for the breeding of niger. This review was provided with a brief explanation of the status of niger breeding and biotechnology aspects and the major challenges facing niger research and production in Ethiopia. Besides, the gap of research was forwarded in this document.


Xs: 4.1653748 Ys: 0.42665988 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: How brand attitude, brand quality, and brand value affect Thai canned tuna consumer brand loyalty abstract: As one of the world's most valuable fish, Tuna can either be found in inexpensive tins on grocery store shelves or on high-end auction blocks destined for Japanese sashimi and sushi restaurants. Moreover, Thailand is reported to be the world's largest exporter of prepared or preserved tuna, which in 2019 contributed an estimated $2.5 billion to Thailand's exports. However, brand research is very limited for canned tuna, especially when it comes to product packaging cues, and how packaging affects a consumer's decision-making process. Therefore, this study set out to investigate which factors play the greatest role in a Thai consumer's brand loyalty (BL) for tuna fish canned products. Research teams using systematic random sampling were dispatched to five supermarkets within the Bangkok metropolitan area and collected 400 questionnaires answering items related to brand attitudes (BA), brand quality (BQ), and brand value (BV) as they related to canned tuna brand loyalty (BL). Thereafter, data analysis of the four constructs and 13 observed variables was conducted with use of LISREL 9.1, which included a confirmatory factor analysis (CFA), a goodness-of-fit (GOF) analysis along with the study's structural equation modeling (SEM). Results determined that there was a positive effect (73% R²) between all the causal factors on Thai canned tuna BL. Furthermore, the factors affecting BL ranked from the greatest to the lowest were BA, BQ, and BV with total effect (TE) values of 0.85, 0.33, and 0.19, respectively. Key takeaways from the study's research seem to indicate that canned tuna is viewed by most consumers as a ‘commodity’, with product availability and convenience being of the utmost importance in product brand selection. Global fishing stocks sustainability, labor costs/practices, and dolphin free catches within the tuna industry were also determined to be important aspects within the international consumer community. Also, due to the demand for high-quality and safe tuna products, adding value has become increasingly important in satisfying consumer demands and represents an opportunity for marketplace expansion.


Xs: 3.7734036 Ys: -0.58209836 Publish year: 2021 keyword: thai__longevity_diet source: Thai title: Mediterranean diet – promotion and dissemination of healthy eating: proceedings of an exploratory seminar at the Radcliffe institute for advanced study abstract: The traditional Mediterranean diet is considered the world’s most evidence-based eating pattern for promoting health and longevity. However, institutional food environments and their busy consumers often sacrifice health benefits for the convenience of faster and cheaper foods that generally are of lower quality and are more processed, and thus, contribute to the current epidemics of obesity and diabetes. Expert consensus has even identified the Mediterranean diet as the easiest to follow among healthy eating patterns. Nonetheless, fewer American families cook at home and many food services have been slow to implement healthier food options compatible with the Mediterranean diet. In September 2019, we convened a group of thought leaders at an exploratory seminar entitled: “Mediterranean Diet: Promotion and Dissemination of Healthy Eating”, hosted by the Radcliffe Institute for Advanced Studies at Harvard University. The multidisciplinary faculty discussed best practices for translating traditional Mediterranean lifestyle principles to modern society.


Xs: 4.9196386 Ys: -0.066159174 Publish year: 2023 keyword: thai__longevity_diet source: Thai title: Measures of Oxidative Status Markers in Relation to Age, Sex, and Season in Sick and Healthy Captive Asian Elephants in Thailand abstract: Oxidative stress is a pathological condition that can have adverse effects on animal health, although little research has been conducted on wildlife species. In this study, blood was collected from captive Asian elephants for the assessment of five serum oxidative status markers (reactive oxygen species (ROS) concentrations; malondialdehyde, MDA; albumin; glutathione peroxidase, GPx; and catalase) in healthy (n = 137) and sick (n = 20) animals. Health problems consisted of weakness, puncture wounds, gastrointestinal distress, eye and musculoskeletal problems, and elephant endotheliotropic herpesvirus hemorrhagic disease (EEHV-HD). Fecal samples were also collected to assess glucocorticoid metabolites (fGCMs) as a measure of stress. All data were analyzed in relation to age, sex, sampling season, and their interactions using generalized linear models, and a correlation matrix was constructed. ROS and serum albumin concentrations exhibited the highest concentrations in aged elephants (>45 years). No sex differences were found for any biomarker. Interactions were observed for age groups and seasons for ROS and catalase, while GPx displayed a significant interaction between sex and season. In pairwise comparisons, significant increases in ROS and catalase were observed in summer, with higher ROS concentrations observed only in the adult female group. Lower catalase activity was exhibited in juvenile males, subadult males, adult females, and aged females compared to subadult and adult elephants (males and females) in winter and the rainy season. There was a positive association between catalase activity and fGCMs (r = 0.23, p < 0.05), and a number of red blood cell parameters were positively associated with several of these biomarkers, suggesting high oxidative and antioxidative activity covary in red cells (p < 0.05). According to health status, elephants with EEHV-HD showed the most significant changes in oxidative stress markers, with MDA, GPx, and catalase being higher and albumin being lower than in healthy elephants. This study provides an analysis of understudied health biomarkers in Asian elephants, which can be used as additional tools for assessing the health condition of this species and suggests age and season may be important factors in data interpretation.


Xs: 3.2646604 Ys: 4.0065703 Publish year: 2018 keyword: thai__longevity_diet source: Thai title: A review on anti-aging properties of probiotics abstract: Aging is the inevitable biological event associated with several physiological, behavioral, and lifestyle events, but people do not wish to become old. The market for anti-aging products is growing gradually, and customers are aware of active principles in the cosmetics. The probiotics are known for several health benefits; especially probiotics regulate the gut health and immune system. Recent studies emphasized the role of probiotics, and probiotic-containing fermented products in cosmetics, and aging. The whole mechanism of aging has not been elucidated yet, but modern aging theories are in two different categories such as programmed theory and damage theory. The aging mechanisms can be discussed in organismal, and cellular level. To some extent, organismal and premature aging is controlled by genetic makeup. Though genetic, and environmental factors impact healthy aging, diet and gut microbiota also play a significant role in senescence. Aging is greatly associated with a diversity of gut microbiota that is often related to the changes in the gastrointestinal tract, and dietary patterns, together with an associated decline in cognitive and immune function, eventually contributing to infirmity. Lactic acid bacteria are reported for the ability to extend the lifespan and/or healthspan. The current manuscript discussed the aging mechanisms, an association of microbiome and aging, and compiled the reported anti-aging properties of probiotics.